Population-Based Prevalence and 5-Year Change of Soft Drusen, Pseudodrusen, and Pachydrusen in a Japanese Population [PDF]
Purpose: To elucidate the prevalence of soft drusen, pseudodrusen, and pachydrusen and their 5-year changes in a Japanese population. Design: Longitudinal population-based cohort study conducted from 2013 through 2017. Participants: Residents 40 years of
Miki Sato-Akushichi, MD +7 more
doaj +5 more sources
Complete Resolution of Central Soft Drusen without Geographic Atrophy or Choroidal Neovascularization. [PDF]
The treatment and prevention of dry age-related macular degeneration (AMD) traditionally involve lifestyle modifications and antioxidant supplementation, including the AREDS2 formula. We present a case of a woman with dry AMD in her right eye with several large, confluent central drusen on her exam and optical coherence tomography B-scan.
Zeng R, Garg I, Miller JB.
europepmc +3 more sources
Long-term Evolution and Remodeling of Soft Drusen in Rhesus Macaques. [PDF]
To characterize the evolution and structure of soft drusen in aged rhesus macaques using in vivo multimodal retinal imaging and ex vivo histologic and ultrastructural analyses as a nonhuman primate model of early age-related macular degeneration (AMD).Multimodal imaging including fundus photography, spectral domain optical coherence tomography (SD-OCT),
Yiu G +9 more
europepmc +5 more sources
Association of soft drusen with risk of all-cause and specific-cause mortality in the National Health and Nutrition Examination Survey, 2005 to 2008 [PDF]
The aim of this study is to investigate the correlation between soft drusen and the likelihood of mortality from all causes and specific ailments within a representative United States population.
Huihui Wu +7 more
doaj +2 more sources
CFH Y402H confers similar risk of soft drusen and both forms of advanced AMD. [PDF]
Age-related macular degeneration (AMD) is the most common cause of irreversible visual impairment in the developed world. The two forms of advanced AMD, geographic atrophy and neovascular AMD, represent different pathological processes in the macula that
Kristinn P Magnusson +21 more
doaj +5 more sources
Drusen-specific dark adaptation profiles in intermediate age-related macular degeneration [PDF]
Aims To investigate the influence of macular drusen phenotypes on dark adaptation (DA) in intermediate age-related macular degeneration (iAMD). Methods This cross-sectional, multicentric study enrolled 57 eyes of 43 iAMD patients.
Paolo Forte +16 more
doaj +2 more sources
ABUNDANCE AND MULTIMODAL VISIBILITY OF SOFT DRUSEN IN EARLY AGE-RELATED MACULAR DEGENERATION: A Clinicopathologic Correlation. [PDF]
Purpose: To determine the abundance and multimodal visibility of drusen and basal linear deposit (BLinD) in early age-related macular degeneration. Methods: A 69-year-old white man was imaged by color fundus photography and red free photography, fundus autofluorescence, and optical ...
Chen L +6 more
europepmc +5 more sources
Multimodal imaging for early drusen detection: RM-SLO as a promising imaging approach [PDF]
PurposeThis study aimed to evaluate the diagnostic performance of retro-mode scanning laser ophthalmoscopy (RM-SLO) in detecting drusen compared to conventional multimodal imaging.
Shujun Zhang +9 more
doaj +2 more sources
Fundus Autofluorescence Lifetimes and Spectral Features of Soft Drusen and Hyperpigmentation in Age-Related Macular Degeneration. [PDF]
To investigate the autofluorescence lifetimes as well as spectral characteristics of soft drusen and retinal hyperpigmentation in age-related macular degeneration (AMD).Forty-three eyes with nonexudative AMD were included in this study. Fluorescence lifetime imaging ophthalmoscopy (FLIO), which detects autofluorescence decay over time in the short (SSC)
Hammer M +8 more
europepmc +3 more sources

