Objective To evaluate multimodal imaging (MMI) biomarkers for predicting progression from intermediate to advanced age-related macular degeneration (AMD).Methods and analysis This prospective longitudinal cohort study included patients with intermediate ...
Alan Palestine +11 more
doaj +1 more source
Introduction: of advanced diagnostic methods shed the light on the variable course of age-related macular degeneration (AMD). Despite establishing AMD classifications used in clinical practice, there are still forms of AMD that do not fit into these ...
Maciej Gawęcki, Andrzej Grzybowski
doaj +1 more source
Retinal drusen: harbingers of age, safe havens for trouble [PDF]
Craig, D. +3 more
core +1 more source
Microtubule motors transport phagosomes in the RPE, and lack of KLC1 leads to AMD-like pathogenesis. [PDF]
The degradation of phagosomes, derived from the ingestion of photoreceptor outer segment (POS) disk membranes, is a major role of the retinal pigment epithelium (RPE). Here, POS phagosomes were observed to associate with myosin-7a, and then kinesin-1, as
Diemer, Tanja +6 more
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Laser treatment of soft drusen in age-related maculopathy. [PDF]
openaire +2 more sources
Mesopic and dark-adapted two-color fundus-controlled perimetry in patients with cuticular, reticular, and soft drusen. [PDF]
Pfau M +8 more
europepmc +1 more source
Antecedents of Soft Drusen, the Specific Deposits of Age-Related Macular Degeneration, in the Biology of Human Macula. [PDF]
Curcio CA.
europepmc +1 more source
Cure or cause: Opposing roles for zinc in age-related macular degeneration [PDF]
Lengyel, I, Peto, T
core
Hyperspectral Imaging for the Classification and Analysis of Drusen in Age-Related Macular Degeneration. [PDF]
Chen C +19 more
europepmc +1 more source
CFH Y402H Confers Similar Risk of Soft Drusen and Both Forms of Advanced AMD.
BACKGROUND: Age-related macular degeneration (AMD) is the most common cause of irreversible visual impairment in the developed world. The two forms of advanced AMD, geographic atrophy and neovascular AMD, represent different pathological processes in the macula that lead to loss of central vision.
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