Integrity of the Hyperreflective Layer in the Inner Choroid in Eyes with Drusen
Ophthalmology and Therapy, 2023 Introduction This study aimed to compare the integrity of the hyperreflective layer of the inner choroid in eyes with and without drusen. Methods Swept-source optical coherence tomography images of patients with drusen and normal controls were reviewed ...
Young Ho Kim, Cheolmin Yun, Jaeryung Oh
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Evolution of soft drusen in age-related macular degeneration [PDF]
Eye, 1994 The pathways by which soft drusen are formed are illustrated by representative clinical and clinicopathological cases. One type is derived from small hard drusen which first tend to aggregate into clusters and then fuse, forming larger deposits termed hard clusters.
J P, Sarks +2 more
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MMP-2 Rs24386 (C-->T) gene polymorphism and the phenotype of age-related macular degeneration [PDF]
International Journal of Ophthalmology, 2017 AIM: To examine the MMP-2 (-1306 C/T) gene polymorphism and the phenotype characterized by soft and hard drusen of early age-related macular degeneration (AMD) and geographic atrophy of late AMD form.
Rasa Liutkeviciene +6 more
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Dynamic soft drusen remodelling in age-related macular degeneration [PDF]
British Journal of Ophthalmology, 2010 To demonstrate and quantify the dynamic remodelling process of soft drusen resorption and new drusen formation in age-related macular degeneration (AMD) with novel interactive methods.Twenty patients with large soft drusen bilaterally and without advanced AMD were imaged at baseline and again at a mean interval of 2 years (40 eyes, 80 images).
R Theodore, Smith +6 more
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Disappearance of soft drusen and subsequent development of choroidal neovascularization following macular hole surgery: a case report. [PDF]
BMC Ophthalmol, 2015 Lee JH, Lee T, Lee SC, Lee CS.
europepmc +2 more sources
In Vivo Multimodal Imaging of Drusenoid Lesions in Rhesus Macaques. [PDF]
, 2017 Nonhuman primates are the only mammals to possess a true macula similar to humans, and spontaneously develop drusenoid lesions which are hallmarks of age-related macular degeneration (AMD).
Cunefare, David +8 more
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An Evaluation of a Battery of Functional and Structural Tests as Predictors of Likely Risk of Progression of Age-Related Macular Degeneration. [PDF]
, 2018 Purpose: To evaluate the ability of visual function and structural tests to identify the likely risk of progression from early/intermediate to advanced AMD, using the Age-Related Eye Disease Study (AREDS) simplified scale as a surrogate for risk of ...
Bailey, C. +3 more
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Identification of hydroxyapatite spherules provides new insight into subretinal pigment epithelial deposit formation in the aging eye. [PDF]
, 2015 Accumulation of protein- and lipid-containing deposits external to the retinal pigment epithelium (RPE) is common in the aging eye, and has long been viewed as the hallmark of age-related macular degeneration (AMD).
Bird, AC +14 more
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Correlation between retinal function and microstructural foveal changes in intermediate age related macular degeneration [PDF]
, 2017 Purpose: To assess foveal microstructural changes influencing retinal sensitivity (RS) and fixation stability using microperimeter MP-1 in intermediate age-related macular degeneration (AMD).
Carnevale, Carmela +3 more
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Age-related macular degeneration eyes presenting with cuticular drusen and reticular pseudodrusen
Scientific Reports, 2022 This study aimed to describe the clinical characteristics of age-related macular degeneration (AMD) eyes with both cuticular drusen (CD) and reticular pseudodrusen (RPD).
Je Moon Yoon +3 more
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