Results 51 to 60 of about 4,519 (191)
Pachydrusen in polypoidal choroidal vasculopathy in an Indian cohort
Indian Journal of Ophthalmology, 2019 Purpose: To report the prevalence of pachydrusen and their relationship with subfoveal choroidal thickness (SFCT) and large choroidal vessel layer thickness (SF-LCVT) in eyes with polypoidal choroidal vasculopathy (PCV) and their fellow eyes.
Sumit Randhir Singh +5 more
doaj +1 more source
Elevated high-density lipoprotein cholesterol and age-related macular degeneration: the Alienor study. [PDF]
PLoS ONE, 2014 BACKGROUND: Lipid metabolism and particularly high-density lipoprotein (HDL) may be involved in the pathogenic mechanism of age-related macular degeneration (AMD). However, conflicting results have been reported in the associations of AMD with plasma HDL
Audrey Cougnard-Grégoire +7 more
doaj +1 more source
A variance components factor model for genetic association studies: a Bayesian analysis.
, 2010 Studies of gene-trait associations for complex diseases often involve multiple traits that may vary by genotype groups or patterns. Such traits are usually manifestations of lower-dimensional latent factors or disease syndromes.
Nonyane, BAS, Whittaker, JC
core +1 more source
Prevalence of age-related macular degeneration in the Republic of Ireland [PDF]
, 2015 Background Age-related macular degeneration (AMD) remains the most common cause of visual loss among subjects over 50 years of age in the developed world.
Akuffo, Kwadwo Owusu +10 more
core +1 more source
Multimodal Imaging of Subfoveal Pachydrusen Containing a Blood Flow Signal
Case Reports in Ophthalmological Medicine, 2022 Individuals with pachydrusen, larger than 125 μm, have a significantly thicker choroid than do those with soft drusen or reticular pseudodrusen. Little is known about cases of abnormal blood flow within pachydrusen.
Naoko Ishiguro +6 more
doaj +1 more source
Evaluation of coronary artery disease as a risk factor for reticular pseudodrusen [PDF]
, 2017 Purpose: Reticular pseudodrusen (RPD) are a risk factor for late age-related macular degeneration (AMD). Associations between RPD and coronary artery disease (CAD) have been reported from small case-control studies.
Baljean Dhillon +27 more
core +4 more sources
PLoS ONE, 2021 PurposeTo evaluate the incidence and risk factors of neovascularization in unaffected fellow eyes of patients diagnosed with type 3 neovascularization in Korea.MethodsThis retrospective study included 93 unaffected fellow eyes of 93 patients diagnosed ...
Jae Hyuck Kwak +5 more
doaj +1 more source
Characterization of age-related macular degeneration in Indian donor eyes
Indian Journal of Ophthalmology, 2021 Purpose: The purpose of this study was to test the reliability of fundus stereomicroscopy in postmortem eyes to assign severity of age-related macular degeneration (AMD) using the Minnesota grading and confirmation by histology using Alabama and Sarks ...
Sudha Priya Soundara Pandi +6 more
doaj +1 more source
Proof of concept, randomized, placebo-controlled study of the effect of simvastatin on the course of age-related macular degeneration [PDF]
, 2013 BACKGROUND: HMG Co-A reductase inhibitors are ubiquitous in our community yet their potential role in age-related macular degeneration (AMD) remains to be determined.
A Mant +49 more
core +3 more sources
Frontiers in Immunology, 2020 Granzymes are a family of serine proteases first shown to be intracellular initiators of immune-mediated cell death in target pathogenic cells. In addition to its intracellular role, Granzyme B (GzmB) has important extracellular functions in immune ...
Joanne A. Matsubara +10 more
doaj +1 more source