Results 41 to 50 of about 340,313 (258)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Fault recovery strategy for urban distribution networks using soft open points

Energy Conversion and Economics
In recent years, the frequent occurrence of natural disasters has seriously threatened the security and stability of distribution networks. Amidst these natural disasters, researchers have increasingly focused on ensuring fault recovery in distribution ...
Liangsheng Lan, Guangqi Liu, Sitong Zhu, Min Hou, Xinrui Liu   +4 more
doaj   +1 more source

Utilizing Soft Open Points for Effective Voltage Management in Multi-Microgrid Distribution Systems

Electricity
To enhance stability and reliability, multi-microgrid systems have been developed as replacements for conventional distribution networks. Traditionally, switches have been used to interconnect these microgrids, but this approach often results in ...
Ali Azizivahed, Khalil Gholami, Ali Arefi, Mohammad Taufiqul Arif, Md Enamul Haque   +4 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Optimal operation of active distribution network considering energy storage-equipped soft open points

e-Prime: Advances in Electrical Engineering, Electronics and Energy
The Soft Open Point (SOP) is a cutting-edge electronic apparatus consisting of voltage source converters linked by a DC capacitor, designed to connect neighbouring distribution feeders.
Samarendra Pratap Singh, Neeraj Kanwar, Amit Saraswat   +2 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Infra Soft Semiopen Sets and Infra Soft Semicontinuity

Journal of Function Spaces, 2021
To contribute to the area of infra soft topology, we introduce one of the generalizations of infra soft open sets called infra soft semiopen sets. We establish some characterizations of them and study their main properties.
Tareq M. Al-shami, A. A. Azzam
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Unified droop control strategy of soft normally open points in AC/DC microgrids

电力工程技术
To address the stable operation issue of AC/DC hybrid microgrids in islanded mode, a unified droop control strategy based on soft normally open point (SNOP) is proposed.
Xinhua YANG, Tong WANG, Xingfeng XIE, Yuhang ZHANG, Xiangjun QUAN   +4 more
doaj   +1 more source