Results 51 to 60 of about 99,858 (272)

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

s̃βs- Open Sets and s̃βs- Continuous in Soft Topological Spaces

Ibn Al-Haitham Journal for Pure and Applied Sciences
Our work introduces the notion of  -open set. This class of - open sets is not directly comparable to the categories of soft open, -closed. We demonstrate that the category of  -open sets lies strictly between the class of -open sets and -open sets ...
Nehmat K. Ahmed, Shaymaa M. Mohammed
doaj   +1 more source

A study on new classes of binary soft sets in topological rough approximation space

Қарағанды университетінің хабаршысы. Математика сериясы, 2023
Soft binary relation is used to define new classes of soft sets, namely BR-soft simply open set and BR-soft simply* alpha open set, in topological rough approximation space over two different universes.
C.R. Parvathy, A. Sofia
doaj   +1 more source

Properties Of New Classes Of ω-µ-Sets In Gts

, 2023
The notions of ω-µ-closed sets and ω-µ-open sets in generalized topological space were introduced and studied by Al Ghour and Zareer. In this paper, we introduce new classes of ω-µ-open sets and continuous functions in topological spaces and study the ...
Rosas, E, Rajalaksmi, R, Rajesh, N, Carpintero, C   +3 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

On Soft Semi-Open Sets and Soft Semi-Continuity in Fuzzifying Soft Topological Spaces [PDF]

Eurasian Journal of Science and Engineering, 2018
In this paper, a new class of soft open sets in fuzzifying soft topological spaces called soft semi open sets is introduced and its fuzzifying soft topological properties is studied and investigated.
Ramadhan A. Mohammed, Tahir H. Ismail, A. A. Allam   +2 more
doaj   +1 more source

Some Games with Soft -ᶅ-Pre-Generalized Open Sets

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2021
In this paper, the concept of soft closed groups is presented using the soft ideal pre-generalized open and soft pre-open, which are -ᶅ- - -closed sets " -closed", Which illustrating several characteristics of these groups.  We also use some games and  
Hammood A. A, Esmaeel R. B
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source