Results 51 to 60 of about 917,408 (205)
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
s̃βs- Open Sets and s̃βs- Continuous in Soft Topological Spaces
Our work introduces the notion of -open set. This class of - open sets is not directly comparable to the categories of soft open, -closed. We demonstrate that the category of -open sets lies strictly between the class of -open sets and -open sets ...
Nehmat K. Ahmed, Shaymaa M. Mohammed
doaj +1 more source
A Note on New Sources of Gaugino Masses [PDF]
In IIB orientifold models, the singlet twisted moduli appear in the tree-level gauge kinetic function. They might be responsible for generating gaugino masses if they acquire non-vanishing F-terms. We discuss some aspects of this new possibility, such as
Benakli, Karim
core +3 more sources
Nearly Soft β - Open Sets via Soft Ditopological Spaces
As a result of the importance of topological space in data analysis and some applications, many researches have used various methods to expand that space, including the concept of ditopology. We define new types of nearly soft open sets in soft ditopology as soft β - open, soft β - closed, soft preopen, soft semi - open, and some related properties ...
Radwan Ahmad Abu-Gdairi +2 more
openaire +2 more sources
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson +3 more
wiley +1 more source
Soft-Decision-Driven Channel Estimation for Pipelined Turbo Receivers [PDF]
We consider channel estimation specific to turbo equalization for multiple-input multiple-output (MIMO) wireless communication. We develop a soft-decision-driven sequential algorithm geared to the pipelined turbo equalizer architecture operating on ...
Yoon, Daejung, Moon, Jaekyun
core +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
On Weak and Strong Forms of Fuzzy Soft Open Sets
We introduce and examined some basic properties of fuzzy soft α-open (closed) sets in fuzzy soft topological spaces. Fuzzy soft pre-open (closed) sets are also defined and discussed.
Sabir Hussain
doaj +1 more source
Hierarchical Models as Marginals of Hierarchical Models
We investigate the representation of hierarchical models in terms of marginals of other hierarchical models with smaller interactions. We focus on binary variables and marginals of pairwise interaction models whose hidden variables are conditionally ...
Montufar, Guido, Rauh, Johannes
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source

