Results 61 to 70 of about 917,408 (205)

Soft i-Open Sets in Soft Bi-Topological Spaces

Al-Qadisiyah Journal of Pure Science, 2023
In our study we introduced soft i-open sets and soft i-star-generalized-w-closed sets in soft bi-topological spaces, , using the notion of soft i-open sets in soft-topological-space, . We besides that give examples to clarify these relationships while presenting some essential characteristics and relationships between various groups of sets.
Sabih Askandar, Beyda S. Abdullah, Luma Khaleel   +2 more
openaire   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

c-Continuity, c-Compact and c-Separation Axioms via Soft Sets [PDF]

Neutrosophic Sets and Systems
This paper focuses on the concept of S c-open sets as a generalization of classical c-open sets in topology. The reason behind introducing S c-open sets is to overcome the limitations of traditional open sets in handling uncertainty and vagueness ...
Gugu Narzary, Bhimraj Basumatary, Giorgio Nordo   +2 more
doaj   +1 more source

On Uniform Capacitated $k$-Median Beyond the Natural LP Relaxation

, 2014
In this paper, we study the uniform capacitated $k$-median problem. Obtaining a constant approximation algorithm for this problem is a notorious open problem; most previous works gave constant approximations by either violating the capacity constraints ...
Li, Shi
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

SUPRA SOFT R-SEPARATION AXIOMS [PDF]

Acta Scientifica Malaysia, 2018
This paper introduces the notion of supra soft b-separation axioms based on the supra b-open soft sets which are more general than supra open soft sets. We investigate the relationships between these supra soft separation axioms.
Tahir Ayaz, Arif Mehmood Khattak, Nisar Ahmad   +2 more
doaj   +1 more source

Approximation of definable sets by compact families, and upper bounds on homotopy and homology

, 2007
We prove new upper bounds on homotopy and homology groups of o-minimal sets in terms of their approximations by compact o-minimal sets. In particular, we improve the known upper bounds on Betti numbers of semialgebraic sets defined by quantifier-free ...
Gabrielov, Andrei, Vorobjov, Nicolai
core   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Soft Topological Space in Virtue of Semi* Open Sets

Universal Journal of Mathematics and Applications, 2020
The ultimate purpose of this research article is to originate and examine some new kind of open sets in soft topological spaces such as soft semi* - open and soft semi* - closed sets using generalized closure operator with illustrating counter examples.
Muneesh Kumar Arumugam, M.lellis Thıvagar, Gnanachandra Prabu   +2 more
doaj   +1 more source