Results 71 to 80 of about 917,408 (205)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

ON SOFT b-I-OPEN SETS WITH RESPECT TO SOFT IDEAL

Journal of New Theory, 2015
Abstaract−The aim of this work is to present and learning a novel set of soft I-open sets, namel soft b-open sets and acquire some of their features. Then debated the relations among soft semi-I- open sets, soft pre-I-open sets, soft β − I-open sets and ...
Fethullah Erol, Alkan Özkan, Metin Akdağ   +2 more
doaj  

UA12/2/1 College Heights Herald, Vol. 53, No. 30 [PDF]

, 1974
WKU campus newspaper reporting campus, athletic and Bowling Green, Kentucky news. Articles in this issue: Cross, Al. Regents Approve Mandatory Housing Appeal Procedure Okayed by Regents Associated Student Government Says Dorm Rule ‘Necessity’ Student-
WKU Student Affairs
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

ON SOFT e-OPEN SETS AND SOFT e-CONTINUITY IN SOFT TOPOLOGICAL SPACE

Journal of New Theory, 2017
In this paper, a new class of generalized soft open sets in soft topological spaces, called soft e-open set is focused and investigated some properties of them.
Anjan Mukherjee, Bishnupada Debnath
doaj  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Neutrosophic Soft $\alpha-$Open Set in Neutrosophic Soft Topological Spaces

, 2020
In this paper, the notion of generalized neutrosophic soft open set (GNSOS) in neutrosophic soft  open set (GNSOS) in neutrosophic soft topological structures relative to neutrosophic soft points is introduced.The concept of generalized neutrosophic soft separation axioms in neutrosophic soft topological spaces with respect to soft points.
Arif Mehmood, Fawad Nadeem, Choonkil Park, Giorgio Nordo, Humaira Kalsoom, Muhammad Rahim Khan, Naeem Abbas   +6 more
openaire   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Soft Generalized αii-Closed Sets in Soft Topological Spaces [PDF]

BIO Web of Conferences
This work presented a novel kind of soft generalized closed sets and soft generalized open sets, which we will call soft generalized αii-closed sets and soft generalized αii-open sets in right now paper.
Dawod Aveen B., Askandar Sabih W.
doaj   +1 more source

Characterization of Bipolar Vague Soft S-Open Sets

Journal of Function Spaces, 2022
This paper concerns the study of the concept of bipolar vague soft s-open set, bipolar vague soft s-interior, bipolar vague soft s-closer, and bipolar vague soft s-exterior in bipolar vague soft topological spaces.
Farkhanda Afzal, Arif Mehmood, Samer Al Ghour, Mudasar Zafar, Hamzah Sakidin, Saeed Gul   +5 more
doaj   +1 more source