Results 41 to 50 of about 307,301 (300)
Sampling rare switching events in biochemical networks
, 2004 Bistable biochemical switches are ubiquitous in gene regulatory networks and signal transduction pathways. Their switching dynamics, however, are difficult to study directly in experiments or conventional computer simulations, because switching events ...
C. Dellago +8 more
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
DC-DC High-Step-Up Quasi-Resonant Converter to Drive Acoustic Transmitters
Energies, 2022 This paper proposes a quasi-resonant step-up DC-DC converter to provide the DC-link voltage for piezoelectric transmitters (PZETs). The resonance not only provides a soft-switching condition for the converter switches, but also helps to decrease the ...
Emad Roshandel +3 more
doaj +1 more source
A novel soft-switching inverter using resonant inductor freewheeling [PDF]
, 1997 A novel topology of the voltage-source soft-switching inverter for induction motor drives is presented. The key of this topology is to employ two fractional-duty auxiliary switches and one resonant inductor per phase to provide a favorable zero-voltage ...
Chan, CC, Chan, DTW, Chau, KT, Yao, JM
core +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Energy Reports, 2023 High-frequency start-up strategy is usually used to limit the current overshoot in the resonant tank of LLC converter. However, the strong coupling among start-up frequency, initial duty cycle, and current limit increases the design complexity of ...
Ning Li +5 more
doaj +1 more source
Performance evaluation of ZVS/ZCS high efficiency AC/DC converter for high power applications [PDF]
Bulletin of the Polish Academy of Sciences: Technical Sciences, 2020 The increased power density, reduced switching losses with minimum electromagnetic interference (EMI), and high efficiency are essential requirements of power converters.
A. Ali +4 more
doaj +1 more source
A microfluidic 2×2 optical switch [PDF]
, 2004 A 2×2 microfluidic-based optical switch is proposed and demonstrated. The switch is made of an optically clear silicon elastomer, Polydimethylsiloxane (PDMS), using soft lithography.
Campbell, Kyle +6 more
core
Magnetic characterization of perpendicular recording media [PDF]
, 2002 In this paper, we describe techniques for the magnetic characterization of perpendicular recording media. Such measurements made using traditional techniques, such as the vibrating sample magnetometry (VSM) and alternating gradient force magnetometer ...
Gustafson, R.W. +7 more
core +1 more source