Results 41 to 50 of about 1,401,689 (359)

PNO1 promotes the progression of osteosarcoma via TGF-β and YAP/TAZ pathway

Scientific Reports, 2023
This study aimed to explore the potential role and mechanisms of the partner of NOB1 homolog (PNO1) in osteosarcoma. The expression of PNO1 in tumor and adjacent tissue samples was examined using western blotting.
Long Fang, Baolong Wang, Zengkun Yang, Tingbao Zhao, Wei Hao   +4 more
doaj   +1 more source

Soft-tissue specimens from pre-European extinct birds of New Zealand [PDF]

, 2012
We provide the first complete review of soft tissue remains from New Zealand birds that became extinct prior to European settlement (c. AD 1800). These rare specimens allow insights into the anatomy and appearance of the birds that are not attainable ...
Fraser, C, Rawlence, Nicolas J., Scofield, R. P., Tennyson, A. J. D., Wood, Jamie R.   +4 more
core   +2 more sources

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

Identification and characterization of mitochondrial autophagy-related genes in osteosarcoma and predicting clinical prognosis

Scientific Reports
Osteosarcoma (OS), the most prevalent primary malignant bone tumor, is characterized by a poor prognosis and high metastatic potential. Mitochondrial autophagy has been implicated in cancer suppression.
Hongliang Zhang, Jingyu Zhang, Kai Zhu, Shuang Li, Jinwei Liu, Boya Guan, Hong Zhang, Changbao Chen, Yancheng Liu   +8 more
doaj   +1 more source

Phase II trial of VEGFR2 inhibitor apatinib for metastatic sarcoma: focus on efficacy and safety

Experimental and Molecular Medicine, 2019
Cancer: Starving sarcomas into submission A drug that inhibits blood vessel growth offers a potentially promising treatment for a class of tumors with a poor prognosis.
Zhichao Liao, Feng Li, Chao Zhang, Lei Zhu, Yehui Shi, Gang Zhao, Xu Bai, Shafat Hassan, Xinyue Liu, Ting Li, Peipei Xing, Jun Zhao, Jin Zhang, Ruwei Xing, Sheng Teng, Yun Yang, Kexin Chen, Jilong Yang   +17 more
doaj   +1 more source

Comparison of seventh and eighth edition of AJCC staging system in melanomas at locoregional stage

World Journal of Surgical Oncology, 2019
Background The eighth edition of the American Joint Committee on Cancer (AJCC) staging system has been effective since January 2018. It has introduced some major changes in the localized/locoregional melanoma classification.
Pawel Teterycz, Iwona Ługowska, Hanna Koseła-Paterczyk, Piotr Rutkowski   +3 more
doaj   +1 more source

Physiotherapists’ perceptions of problematic musculoskeletal soft tissue disorders [PDF]

, 2008
Original article can be found at: http://www.ijtr.co.uk/ Copyright MA Healthcare Limited.Aims: Many common musculoskeletal disorders are resistant to existing management strategies,causing long-term pain and disability.
Byrne, G., Poltawski, L., Watson, T.
core   +1 more source

Soft-tissue Sarcomas

Indian Journal of Orthopaedics, 2018
This article discusses the epidemiology, diagnosis, and management of primary soft-tissue sarcomas (STS). These musculoskeletal tumors are a rare and heterogeneous group of malignancies, which are best managed by multidisciplinary teams in specialist sarcoma referral centers.
Vodanovich, Domagoj Ante, M Choong, Peter F   +1 more
openaire   +3 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The fusion gene LRP1–SNRNP25 drives invasion and migration by activating the pJNK/37LRP/MMP2 signaling pathway in osteosarcoma

Cell Death Discovery
Through transcriptome sequencing, we previously identified a new osteosarcoma-specific, frequent fusion gene, LRP1–SNRNP25, and found that it played an important role in tumor cell invasion and migration.
Peipei Xing, Haotian Liu, Wanyi Xiao, Gengpu Zhang, Chao Zhang, Zhichao Liao, Ting Li, Jilong Yang   +7 more
doaj   +1 more source