Results 21 to 30 of about 447,491 (216)

Zalecenia Polskiej Grupy Mięsakowej odnośnie postępowania diagnostyczno-terapeutycznego oraz kontroli u chorych na neurofibromatozę typu 1 (NF1) oraz malignant peripheral nerve sheath tumor związany z NF1

Nowotwory, 2022
Neurofibromatoza typu 1 (zespół NF1 in. choroba Recklinghausena, nerwiakowłókniakowatość typu 1), jest dziedziczona autosomalnie dominująco, a odpowiadają za nią mutacje genu NF1 kodującego białko neurofibrominy.
Piotr Rutkowski, Anna Raciborska, Anna Szumera-Ciećkiewicz, Paweł Sobczuk, Mateusz Spałek, Hanna Koseła-Paterczyk, Iwona Ługowska, Katarzyna Bilska, Monika Gos, Janusz Ryś, Ewa Chmielik, Andrzej Tysarowski, Konrad Zaborowski, Małgorzata Oczko-Wojciechowska, Patrycja Castaneda-Wysocka, Donata Makuła, Marcin Zdzienicki, Marcin Ziętek, Piotr Fonrobert, Kamil Dolecki, Marek Dedecjus, Anna M. Czarnecka   +21 more
doaj   +1 more source

Epithelioid sarcoma

Nowotwory, 2023
Epithelioid sarcoma (ES) is a very rare sarcoma characterized by loss of INI1. Enzinger first described ES in 1970, butthe histopathologic differential diagnosis of ES remains challenging.
Anna M. Czarnecka
doaj   +1 more source

Modern Dressings in Prevention and Therapy of Acute and Chronic Radiation Dermatitis—A Literature Review

Pharmaceutics, 2022
Radiotherapy is an integral part of modern oncology, applied to more than half of all patients diagnosed with cancer. It can be used alone or in combination with surgery or chemotherapy.
Konrad Zasadziński, Mateusz Jacek Spałek, Piotr Rutkowski   +2 more
doaj   +1 more source

Safety and Efficacy of Anlotinib, a Multikinase Angiogenesis Inhibitor, in Patients with Refractory Metastatic Soft-Tissue Sarcoma

Clinical Cancer Research, 2018
Purpose: The prognosis for patients with refractory soft-tissue sarcoma (STS) is dismal. Anlotinib has previously shown antitumor activity on STS in preclinical and phase I studies.
Y. Chi, Z. Fang, X. Hong, Yang Yao, P. Sun, Guo-wen Wang, F. Du, Yongkun Sun, Qiong Wu, G. Qu, Shusen Wang, Jianmin Song, Jianchun Yu, Yongkui Lu, Xia Zhu, X. Niu, Zhiyong He, Jinwan Wang, Hao Yu, Jianqiang Cai   +19 more
semanticscholar   +1 more source

Immunotherapy in sarcoma

Nowotwory, 2020
The introduction of immunotherapy with checkpoint inhibitors into clinical practice has radically changed the treatment and prognosis of patients with cancer.
Hanna Koseła-Paterczyk
doaj   +1 more source

Retrospective audit of 957 consecutive 18F-FDG PET–CT scans compared to CT and MRI in 493 patients with different histological subtypes of bone and soft tissue sarcoma

Clinical Sarcoma Research, 2018
BackgroundThe use of 18F-FDG PET–CT (PET–CT) is widespread in many cancer types compared to sarcoma. We report a large retrospective audit of PET–CT in bone and soft tissue sarcoma with varied grade in a single multi-disciplinary centre.
R. Macpherson, S. Pratap, H. Tyrrell, M. Khonsari, Shaun R Wilson, M. Gibbons, D. Whitwell, H. Giele, P. Critchley, Lucy Cogswell, S. Trent, N. Athanasou, K. Bradley, A. Hassan   +13 more
semanticscholar   +1 more source

Tebentafusp (IMCgp100) in the treatment of uveal melanoma — from preclinical evidence to clinical practice

Nowotwory
Tebentafusp (IMCgp100) is a novel bispecific immunotherapy that contains a specifically engineered soluble T-cellreceptor (TCR) capable of recognising the gp100 epitope on the surface of tumour cells presented by human leukocyteantigen-A*02:01 (HLA- A*02:
Piotr Remiszewski, Eryk Siedlecki, Julia Wąż, Kinga Filipek, Agata Pisklak, Wiktor Gaik, Monika Dudzisz-Śledź, Piotr Rutkowski, Anna M. Czarnecka   +8 more
doaj   +1 more source

Single-cell multi-omics elucidates the role of RPS27-RPS24 fusion gene in osteosarcoma chemoresistance and metabolic regulation

Cell Death Discovery
Osteosarcoma (OS) presents significant treatment challenges due to chemoresistance. This study explores the molecular mechanisms underlying chemoresistance in OS, focusing on the novel fusion gene RPS27-RPS24. Using single-cell multi-omics techniques, we
Zhiwei Tao, Pingan Zou, Zhengxu Yang, Tao Xiong, Zhi Deng, Qincan Chen   +5 more
doaj   +1 more source

LncRNAs regulates cell death in osteosarcoma

Scientific Reports
Despite improvements, prognosis in osteosarcoma patients remains poor, making it essential to identify additional and more robust therapeutic targets. Non-apoptotic receptor-mediated cell death (RCD), which plays a crucial role in the pathogenesis of OS,
Ping’an Zou, Zhiwei Tao, Zhengxu Yang, Tao Xiong, Zhi Deng, Qincan Chen, Li Niu   +6 more
doaj   +1 more source

iCREATE: imaging features of primary and metastatic alveolar soft part sarcoma from the EORTC CREATE study

Cancer Imaging, 2020
Background Alveolar Soft Part Sarcoma (ASPS) is a rare, slow-growing, but highly vascular soft tissue sarcoma, characterised by a high rate of metastases at presentation.
Naami Charlotte Mcaddy, Hind Saffar, Saskia Litière, Pieter Jespers, Patrick Schöffski, Christina Messiou   +5 more
doaj   +1 more source