Results 41 to 50 of about 114,138 (120)

Choosing the right animal model for sarcoma research

Cellular and Molecular Life Sciences
Sarcomas comprise over 100 mesenchymal malignancies characterised by extreme genomic heterogeneity, ranging from fusion-driven paediatric tumours to highly unstable adult leiomyosarcomas. This genetic complexity shapes tumour behaviour, influences growth
Piotr Remiszewski, Eryk Siedlecki, Marlena Wełniak-Kamińska, Michał Mikula, Anna Czarnecka   +4 more
doaj   +1 more source

Mechanisms of Resistance to Anti-PD-1 Immunotherapy in Melanoma and Strategies to Overcome It

Biomolecules
Resistance to anti-PD-1 therapy in melanoma remains a major obstacle in achieving effective and durable treatment outcomes, highlighting the need to understand and address the underlying mechanisms.
Magdalena K. Zielińska, Magdalena Ciążyńska, Dorota Sulejczak, Piotr Rutkowski, Anna M. Czarnecka   +4 more
doaj   +1 more source

Sarcomatoid Renal Cell Carcinoma: A Clinical Review

Diagnostics
This review summarises current evidence on renal cell carcinoma (RCC) with sarcomatoid dedifferentiation (sRCC), with an emphasis on diagnosis, prognostic stratification, and treatment. Sarcomatoid dedifferentiation is characterised by high-grade spindle
Piotr Remiszewski, Anna Szumera-Ciećkiewicz, Anna M. Czarnecka   +2 more
doaj   +1 more source

Nectins and Nectin-like molecules in cancer: expression, function, and therapeutic implications in melanoma, lung cancer, and renal cell carcinoma

Oncology in Clinical Practice
Nectins and nectin-like molecules (Necls) are calcium-independent immunoglobulin-like cell adhesion molecules with emerging roles in cancer biology, immune regulation, and targeted therapy.
Anna M. Czarnecka, Michał Nizio, Anna Szumera-Ciećkiewicz, Magdalena Knetki-Wróblewska, Ewa Bartnik, Piotr J. Błoński, Piotr Rutkowski   +6 more
doaj   +1 more source

Outcomes of Talimogene Laherparepvec in Soft Tissue Sarcoma. [PDF]

J Surg Oncol
Williams TP, Catalano S, Liebner DA, Grignol VP.   +3 more
europepmc   +1 more source

Challenging the Conventional Wisdom Around Doxorubicin in Soft Tissue Sarcoma. [PDF]

JCO Oncol Pract
Stein JN, Woodcock MG, Chen KY.
europepmc   +1 more source

The greatest achievements in oncology in 2022 – melanoma and skin carcinomas

Archives of Medical Science, 2022
Piotr Rutkowski
doaj   +1 more source

Biomarkers of prognosis and pazopanib response in soft tissue sarcoma: An exploratory analysis. [PDF]

Ther Adv Med Oncol
Mondaza-Hernandez JL, Amian-Ruiz R, Antonio Cordero Varela J, Carrera-Haro MA, Rodriguez MC, Lopez-Alvarez M, Villar VH, Ramos R, Valverde C, Cruz J, Martinez-Trufero J, Diaz-Beveridge R, Hindi N, Fernandez-Serra A, Lopez-Guerrero JA, Moura DS, Martin-Broto J.   +16 more
europepmc   +1 more source

The impact of pazopanib and extremity radiotherapy on transaminase elevations in soft tissue sarcoma. [PDF]

Acta Oncol
Van Riet BHG, Hassan S, De Wijkerslooth TR, Seijkens TTP, Huitema ADR, Steeghs N, Haas RL.   +6 more
europepmc   +1 more source

Appendicular Soft Tissue Sarcoma Surgery in the Era of Orthoplastics. [PDF]

Cancers (Basel)
Leitão I, Soares do Brito J, Esperança-Martins M, Melo-Alvim C, Lopes-Brás R, Jordão D, Abrunhosa-Branquinho A, Pina F, Lopez-Presa D, Vicente Saraiva L, Turpin A, Portela J.   +11 more
europepmc   +1 more source