Results 31 to 40 of about 110,250 (249)

Proton beam therapy in paediatric cancer: Anticipating the opening of the Australian Bragg Centre for Proton Therapy and Research

Journal of Medical Imaging and Radiation Oncology, EarlyView., 2023
Summary Proton Beam Therapy (PBT) has the potential to improve paediatric cancer care by reducing radiation exposure and thus long‐term toxicities. Ethical concerns and debates surrounding the treatment, such as eligibility and accessibility, are ongoing in Australia. The Australian Bragg Centre for Proton Therapy and Research (ABCPTR) (named after Sir
Jeremy Khong, Hui Tee, Peter Gorayski, Hien Le, Michael Penniment, Sophie Jessop, Jordan Hansford, Melanie Penfold, Julia Green, Kelly Skelton, Frank Saran   +10 more
wiley   +1 more source

Lymph node metastases, sentinel lymph node biopsy, and lymphadenectomy in soft tissue sarcoma — when and why?

Oncology in Clinical Practice
The spread of soft tissue sarcomas (STS) through the lymphatic system occurs rarely, mainly in epithelioid sarcoma, angiosarcoma, rhabdomyosarcoma, and clear cell sarcoma (CARE). STS subtypes differ in terms of biological behavior.
Ada Niezgoda, Anna M. Czarnecka, Paulina Chmiel, Maria Krotewicz, Mateusz Spałek, Tomasz Świtaj, Paweł Rogala, Piotr Rutkowski   +7 more
doaj   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Modern Dressings in Prevention and Therapy of Acute and Chronic Radiation Dermatitis—A Literature Review

Pharmaceutics, 2022
Radiotherapy is an integral part of modern oncology, applied to more than half of all patients diagnosed with cancer. It can be used alone or in combination with surgery or chemotherapy.
Konrad Zasadziński, Mateusz Jacek Spałek, Piotr Rutkowski   +2 more
doaj   +1 more source

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

Advanced Materials, EarlyView.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou, Yalei Hu, Jie Yu, Naoki Komatsu, Yuta Nishina, Alberto Bianco   +5 more
wiley   +1 more source

Outcomes of systemic treatment in advanced melanoma after progression on anti–PD-1 therapy: a real-world study with literature review

Oncology in Clinical Practice
INTRODUCTION: Currently, a substantial proportion of patients are still treated with first-line anti-PD-1 immunotherapy (ICI). After disease progression, treatment options, especially for patients with BRAF-negative tumors, are limited.
Piotr J. Błoński, Krzysztof Ostaszewski, Barbara Buchalska, Julia Szymkiewicz, Tomasz Switaj, Paweł Rogala, Katarzyna Kozak, Monika Dudzisz-Śledź, Anna M. Czarnecka   +8 more
doaj   +1 more source

Bone and Soft Tissue Sarcoma [PDF]

Cancers, 2020
Bone and soft-tissue sarcomas are relatively rare tumors both in children and adults [...]
openaire   +2 more sources

Harnessing MDM2‐Mediated Targeted Degradation of Transcriptional and Epigenetic Machinery to Disrupt Oncogenic Addictions in Pediatric Sarcoma

Advanced Science, EarlyView.
MDM2 dependency in pediatric sarcomas is driven by a novel p53‐independent oncogenic cistrome alongside canonical p53 pathway suppression. This study introduces MDM2‐recruiting transcriptional and epigenetic machinery degraders (MDM2‐TEMADs) as a novel precision oncology modality.
Jiawei Zhou, Xian Guan, Nan Li, Ying Zhang, Long Xie, Xingze Huang, Zhipeng Zhu, Zhuolin Ren, Xiaoyan Yu, Hanjun Guo, Yuanfang Wu, Lin Ma, Suya Zheng, Jingyao Zhang, Jiyang Liu, Victor Kuanmin Lee, Wenhao Chen, H. Phillip Koeffler, Jinhu Wang, Xin Han, Ye Chen, Liang Xu   +21 more
wiley   +1 more source

Systemic inflammation index is a predictive and prognostic factor in patients with liposarcoma or leiomyosarcoma treated with trabectedin

Scientific Reports
Trabectedin is a chemotherapeutic agent that has shown activity in the treatment of patients with soft tissue sarcomas after failure of anthracycline-based therapy and the best results were recorded in the treatment of L-sarcomas.
Pawel Sobczuk, Paulina Filipowicz, Lukasz Lamparski, Hanna Kosela-Paterczyk, Pawel Teterycz, Katarzyna Kozak, Paweł Rogala, Tomasz Świtaj, Sławomir Falkowski, Piotr Rutkowski   +9 more
doaj   +1 more source

Cardiac tumor as first presentation of melanoma

Oncology in Clinical Practice
Melanoma metastases most commonly involve the skin, lungs, central nervous system, and liver. In 1.8% of all patients with melanoma, cardiac metastases are diagnosed.
Magdalena K. Zielińska, Monika Dudzisz-Śledź, Krzysztof Ostaszewski, Aneta Borkowska, Anna M. Czarnecka   +4 more
doaj   +1 more source