Results 61 to 70 of about 150,928 (204)

Efficacy of radiotherapy and radiotherapy with hyperthermia to delay change of systemic therapy in patients with metastatic melanoma

Clinical and Translational Radiation Oncology
Background: The use of radiotherapy (RT) and RT with hyperthermia (HT) as a local treatment for oligoprogression in many tumors is becoming increasingly prevalent.
Paulina Chmiel, Mateusz Jacek Spałek, Hanna Koseła-Paterczyk, Piotr Łukasz Rutkowski, Paulina Jagodzińska-Mucha, Paweł Rogala, Katarzyna Kozak, Maria Telejko, Aneta Maria Borkowska   +8 more
doaj   +1 more source

Rare case of clear cell sarcoma in a young female [PDF]

, 2010
Clear Cell Sarcoma of Tendon and Aponeuroses (CCTA), also known as Melanoma of soft tissue is a rare and highly malignant soft tissue neoplasm which mostly occurs in young adults A 26-year-old female presented with pain and thickened soft tissue in the ...
Bahador, Farshad Michael, Egner, James, Khaliq, Waseem, Musselman, Mark S., Uzoaru, Ikechukwu   +4 more
core  

From pathogenesis to the patient’s bedside: a comprehensive review of extraskeletal myxoid chondrosarcoma

Journal of Cancer Research and Clinical Oncology
Extraskeletal myxoid chondrosarcoma (EMC) is characterised by recurrent NR4A3 gene rearrangements, most commonly EWSR1::NR4A3, and accounts for approximately 1–3% of soft-tissue sarcomas (STS). It typically arises in the deep soft tissues of the proximal
Piotr Remiszewski, Sławomir Falkowski, Anna Szumera-Ciećkiewicz, Mateusz J. Spałek, Piotr Rutkowski, Anna M. Czarnecka   +5 more
doaj   +1 more source

Molecular and Clinicopathological Biomarkers in the Neoadjuvant Treatment of Patients with Advanced Resectable Melanoma

Biomedicines
Neoadjuvant systemic therapy is emerging as the best medical practice in patients with resectable stage III melanoma. As different regimens are expected to become available in this approach, the improved optimization of treatment strategies is required ...
Piotr J. Błoński, Anna M. Czarnecka, Krzysztof Ostaszewski, Anna Szumera-Ciećkiewicz, Piotr Rutkowski   +4 more
doaj   +1 more source

Soft tissue sarcomas at a glance: clinical, histological, and MR imaging features of malignant extremity soft tissue tumors [PDF]

, 2009
Soft tissue sarcomas comprise approximately 1% of malignant tumors. There are more than 50 subtypes, but pleomorphic sarcoma, liposarcoma, leiomyosarcoma, synovial sarcoma, and malignant peripheral nerve sheath tumor account for 75%.
Dijke, C.F. (Cornelis) van, Kliffen, M. (Mike), Krestin, G.P. (Gabriel), Vliet, M.H. (Martin) van   +3 more
core   +3 more sources

Phase Ib/II Study of the Safety and Efficacy of Combination Therapy with Multikinase VEGF Inhibitor Pazopanib and MEK Inhibitor Trametinib In Advanced Soft Tissue Sarcoma. [PDF]

, 2017
Purpose: Pazopanib, a multireceptor tyrosine kinase inhibitor targeting primarily VEGFRs1–3, is approved for advanced soft tissue sarcoma (STS) and renal cell cancer. Downstream of VEGFR, trametinib is an FDA-approved MEK inhibitor used for melanoma.
Azad, Nilofe A., Kurzrock, Razelle, Ludwig, Joseph A., Meric-Bernstam, Funda, Meyer, Christian, O\u27Connor, Ashley, Roszik, Jason, Shaw, Kenna, Subbiah, Vivek, Zahurak, Marianna L., Zinner, Ralph G.   +10 more
core   +1 more source

The significance of margins in pediatric Non‐Rhabdomyosarcoma soft tissue sarcomas: Consensus on surgical margin definition harmonization from the INternational Soft Tissue SaRcoma ConsorTium (INSTRuCT)

Cancer Medicine, 2023
Background Margin status following surgery in children, adolescents, and young adults with soft tissue sarcomas is controversial and has been defined differently by various specialties, with definitions changing over time and by cooperative group.
Monika Sparber‐Sauer, Andrea Ferrari, Sheri L. Spunt, Christian Vokuhl, Dana Casey, Timothy B. Lautz, William H. Meyer, David O. Walterhouse, Kristian W. Pajtler, Rita Alaggio, Andreas Schmidt, Akmal Safwat, Beate Timmermann, Patrizia Dall'Igna, Sonja Chen, Aaron R. Weiss, Daniel Orbach   +16 more
doaj   +1 more source

UK guidelines for the management of soft tissue sarcomas [PDF]

, 2016
Soft tissue sarcomas (STS) are rare tumours arising in mesenchymal tissues, and can occur almost anywhere in the body. Their rarity, and the heterogeneity of subtype and location means that developing evidence-based guidelines is complicated by the ...
Dangoor, A, Gerrand, C, Grimer, R, Judson, I, Seddon, B, Whelan, J   +5 more
core   +1 more source

Biphasic synovial sarcoma in the cervical spine: Case report [PDF]

, 2011
Synovial sarcoma is a rare malignant neoplasm of soft tissue that typically arising near large joints of the upper and lower extremities in young adult males. Only 3% of these neoplasms have been found to arise in the head and neck region.
Stephen M Foreman, Michael J Stahl
core   +1 more source

PI3K/AKT/mTOR inhibition in combination with doxorubicin is an effective therapy for leiomyosarcoma. [PDF]

, 2016
BackgroundLeiomyosarcoma (LMS) is a common type of soft tissue sarcoma that responds poorly to standard chemotherapy. Thus the goal of this study was to identify novel selective therapies that may be effective in leiomyosarcoma by screening cell lines ...
Al-Awar, Rima, Babichev, Yael, Boutros, Paul C, Datti, Alessandro, Dickson, Brendan C, Gladdy, Rebecca A, Isaac, Methvin, Kabaroff, Leah, Prakesch, Michael, Sun, Ren X, Uehling, David, Venier, Rosemarie   +11 more
core   +2 more sources