Results 91 to 100 of about 54,945 (291)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Anomaly Detection in Software-Defined Networking Using Machine Learning

Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2019
In recent years, the Software-Defined Networking (SDN) approach has emerged that aims to make computernetworks more flexible. Although the SDN application on Google's internal network demonstrates the usefulnessof the Software-Defined Network approach ...
Soumaine Bouba Mahamat, Celal Çeken
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Software Defined Networking (Dagstuhl Seminar 12363)

, 2013
This report documents the talks and discussions of Dagstuhl Seminar 12363 "Software Defined Networking". The presented talks represent a spectrum of industrial and academic work as well as both technical and organizational developments surrounding ...
Koponen, Teemu, Hui, Pan
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Software Defined Networking: an emerging paradigm to computer networking [PDF]

, 2017
Software Defined Networking (SDN) is an emerging paradigm in networking technology that enables innovation on how network systems are managed and designed. SDN plays a huge role in the effort to make computer networks programmable.
Oladunjoye, Olanrewaju
core  

Cognitive Software-Defined Networking Using Fuzzy Cognitive Maps

, 2019
Future networks are expected to provide improved support for several different kinds of applications and services. All these services will have diverse characteristics and requirements to be satisfied.
Giovanni Baggio, Fabrizio Granelli, Riccardo Bassoli   +2 more
core   +1 more source

Software-Defined Wireless Mesh Networking

, 2022
S.1520-1535The combination of Software-Defined Networking (SDN) and Wireless Mesh Network (WMN) is challenging due to the different natures of both concepts. SDN describes networks with homogeneous, static and centralized controlled topologies.
Kessel, M., Schlebusch, M., Jonas, K., Rzyska, A., Rademacher, M., Siebertz, F.   +5 more
core   +1 more source

Flexible open network operating system architecture for implementing higher scalability using disaggregated software‐defined optical networking

IET Networks
The enhanced capacity of optical networks is a significant advantage within the global telecommunications industry. Optical networks provides transmission of information over large distances with reduced latency. However, the growing intricacy of network
Kenneth Nsafoa‐Yeboah, Eric Tutu Tchao, Benjamin Kommey, Andrew Selasi Agbemenu, Griffith Selorm Klogo, Nana Kwadwo Akrasi‐Mensah   +5 more
doaj   +1 more source

Improving Internet of Things (IoT) Security with Software-Defined Networking (SDN)

Computers, 2020
There has been an increase in the usage of Internet of Things (IoT), which has recently become a rising area of interest as it is being extensively used for numerous applications and devices such as wireless sensors, medical devices, sensitive home ...
Abdullah Al-Hayajneh, Zakirul Alam Bhuiyan, Ian McAndrew   +2 more
doaj   +1 more source