Results 81 to 90 of about 54,945 (291)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Survey: Intrusion Detection System in Software-Defined Networking
IEEE AccessIn the rapidly evolving field of network architecture, Software-Defined Networking (SDN) has emerged as a transformative approach, providing unprecedented flexibility and control over network resources.
Ahmed H. Janabi +2 more
doaj +1 more source
Evaluation of a Wireless Transport Network Emulator Used for SDN Applications Development
IEEE Access, 2018 Software Defined Networking (SDN) is a paradigm that emerged in the networking industry recently. Many standardization activities are still ongoing and having the right tools to support these efforts is important.
Alexandru Stancu +2 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Design, Implementation and Evaluation of an In-House Controller for Software Defined Networking with Applications [PDF]
, 2017 Over the past several decades, there has been a dramatic improvement in net- working technologies. Network devices and protocols are becoming more powerful and complex. The vertical structure of the network protocol layers also leads to a coupled control
Xu, Yiming
core
The Role of Software-Defined Networking in Cellular Networks
Proceedings, 2019 In this paper, we discuss how SDN can contribute to enhance future cellular networks. We first present SDN and describe its characteristics. Then, we explore how SDN can be used to improve current cellular networks, analyzing the advantages and ...
Pablo Fondo-Ferreiro +1 more
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Automatic failure recovery for software-defined networks [PDF]
, 2013 Tolerating and recovering from link and switch failures are fundamental requirements of most networks, including Software-Defined Networks (SDNs). However, instead of traditional behaviors such as network-wide routing re-convergence, failure recovery in ...
Marco Canini +13 more
core +1 more source