Results 91 to 100 of about 1,453,224 (286)

On the security of software-defined next-generation cellular networks [PDF]

, 2016
In the recent years, mobile cellular networks are ndergoing fundamental changes and many established concepts are being revisited. Future 5G network architectures will be designed to employ a wide range of new and emerging technologies such as Software ...
Alzahrani, Bander, Logothetis, Michael, Moscholios, Ioannis, Vassilakis, Vassilios   +3 more
core  

Fast Recovery in Software-Defined Networks

2014 Third European Workshop on Software Defined Networks, 2014
Although Software-Defined Networking and its implementation OpenFlow facilitate managing networks and enable dynamic network configuration, recovering from network failures in a timely manner remains non-trivial. The process of (a) detecting the failure, (b) communicating it to the controller and (c) recomputing the new shortest paths may result in an ...
Van Adrichem, N.L.M. (author), Van Asten, B.J. (author), Kuipers, F.A. (author)   +2 more
openaire   +4 more sources

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

A Software Defined Networking-Oriented Security Scheme for Vehicle Networks

IEEE Access, 2018
In the intelligent transportation system (ITS), vehicle networks (VNs) can well solve the network related problems. However, as VNs are expected to have a wide range of applications in future services, security challenges are widely recognized ...
Rong Geng, Xiaojie Wang, Jun Liu
doaj   +1 more source

Verifiably-safe software-defined networks for CPS [PDF]

, 2012
Next generation cyber-physical systems (CPS) are expected to be deployed in domains which require scalability as well as performance under dynamic conditions.
Bestavros, Azer, Kfoury, Assaf, Lapets, Andrei, Skowyra, Rick   +3 more
core  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

NeuRoute: Predictive Dynamic Routing for Software-Defined Networks

, 2017
This paper introduces NeuRoute, a dynamic routing framework for Software Defined Networks (SDN) entirely based on machine learning, specifically, Neural Networks.
Azzouni, Abdelhadi, Boutaba, Raouf, Pujolle, Guy   +2 more
core   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source