Results 101 to 110 of about 14,659,030 (367)

Simulating wind effect on microsprinkler water distribution

open access: yesScientia Agricola, 2003
Wind incidence can affect microsprinkler water distribution. Evaluations of those conditions can be facilitated using simulations by computational models.
Marco Antônio Fonseca Conceição   +1 more
doaj  

NFBLab—A Versatile Software for Neurofeedback and Brain-Computer Interface Research

open access: yesFrontiers in Neuroinformatics, 2018
Neurofeedback (NFB) is a real-time paradigm, where subjects learn to volitionally modulate their own brain activity recorded with electroencephalographic (EEG), magnetoencephalographic (MEG) or other functional brain imaging techniques and presented to ...
Nikolai Smetanin   +4 more
doaj   +1 more source

Sustainable Software Ecosystems: Software Engineers, Domain Scientists, and Engineers Collaborating for Science

open access: yes, 2014
The development of scientific software is often a partnership between domain scientists and scientific software engineers. It is especially important to embrace these collaborations when developing advanced scientific software, where sustainability ...
Hanwell, Marcus D.   +2 more
core   +2 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Parallel programming software package GraphPlus Templet

open access: yesVestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2011
The parallel programming automation software package named Graphplus templet is considered. Its design purposes, architecture, efficiency of applying for numerical modeling problems solutions, features against similar approaches are discussed.
Sergey V Vostokin   +2 more
doaj  

Technologies for Cognitive Training and Cognitive Rehabilitation for People With Mild Cognitive Impairment and Dementia. A Systematic Review

open access: yesFrontiers in Psychology, 2020
Due to the growing number of older adults with cognitive impairment, it is essential to delay the onset and progression of cognitive decline and promote a healthy lifestyle.
Eider Irazoki   +9 more
doaj   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Principles of Antifragile Software

open access: yes, 2017
The goal of this paper is to study and define the concept of "antifragile software". For this, I start from Taleb's statement that antifragile systems love errors, and discuss whether traditional software dependability fits into this class. The answer is
Conway M. E.   +3 more
core   +2 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

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