Results 81 to 90 of about 4,685,278 (250)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Вестник Дагестанского государственного технического университета: Технические наукиObjective. The purpose of the study is to theoretically analyze security defects and study the criticality of vulnerabilities in software used in modern automated systems of internal affairs agencies.Method.
I. G. Drovnikova, A. D. Popova
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Heron, a Knowledge Graph editor for intuitive implementation of Python-based experimental pipelines
eLifeTo realise a research project, experimenters face conflicting design and implementation choices across hardware and software. These include balancing ease of implementation – time, expertise, and resources – against future flexibility, the number of ...
George Dimitriadis +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
О ВЫБОРЕ МОДЕЛЕЙ, СРЕДСТВ ДЛЯ СИМУЛЯТОРА АВТОМОБИЛЯ СО СМЕШАННОЙ РЕАЛЬНОСТЬЮ
Cifra: Информационные технологии и телекоммуникацииПроанализированы используемые пакеты для MR, модели движения, колебаний и управляемости, требования к ним при использовании смешанной реальности при моделировании автомобиля.Рассмотрено создание визуализации имитационной обстановки в пакетах Unity ...
Михайлов В.Г.
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Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
TwinP2G: A Software Application for Optimal Power-to-Gas Planning
Future InternetThis paper presents TwinP2G, a software application for optimal planning of investments in power-to-gas (PtG) systems. TwinP2G provides simulation and optimization services for the techno-economic analysis of user-customized energy networks.
Eugenia Skepetari +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source