Results 71 to 80 of about 4,879,388 (250)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

О ВЫБОРЕ МОДЕЛЕЙ, СРЕДСТВ ДЛЯ СИМУЛЯТОРА АВТОМОБИЛЯ СО СМЕШАННОЙ РЕАЛЬНОСТЬЮ

Cifra: Информационные технологии и телекоммуникации
Проанализированы используемые пакеты для MR, модели движения, колебаний и управляемости, требования к ним при использовании смешанной реальности при моделировании автомобиля.Рассмотрено создание визуализации имитационной обстановки в пакетах Unity ...
Михайлов В.Г.
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

TwinP2G: A Software Application for Optimal Power-to-Gas Planning

Future Internet
This paper presents TwinP2G, a software application for optimal planning of investments in power-to-gas (PtG) systems. TwinP2G provides simulation and optimization services for the techno-economic analysis of user-customized energy networks.
Eugenia Skepetari, Sotiris Pelekis, Hercules Koutalidis, Alexandros Menelaos Tzortzis, Georgios Kormpakis, Christos Ntanos, Dimitris Askounis   +6 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Reliability of 2D motion analysis software for evaluation of dynamic smile asymmetry using smartphone technology

Clinical and Investigative Orthodontics
Aim To evaluate the reliability of a free motion analysis method in the evaluation of the 2D dynamic asymmetry of smiles using smartphone technology.Materials and methods Twenty-six healthy adult females were included in this study. Four facial bilateral
Dhelal Al-Rudainy, Hadeel Adel Al-Lami, Talib Al-Ameri, Liu Yang   +3 more
doaj   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

ReSurfEMG: A Python Package for Comprehensive Analysis of Respiratory Surface EMG

Sensors
In patients with respiratory failure, mechanical ventilation aims to balance respiratory muscle loading and gas exchange. The interplay between the ventilator and the respiratory muscles is an increasingly recognized factor in tailoring ventilatory ...
Robertus Simon Petrus Warnaar, Candace Makeda Moore, Walter Baccinelli, Farnaz Soleimani, Dirk Wilhelm Donker, Eline Oppersma   +5 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Artifical Intelligence and the End of the Author

Umanistica Digitale
Although artificial intelligence and generative artificial intelligence have outstanding achievements, evaluating their possibilities and drawbacks is still problematic.
Umberto Roncoroni
doaj   +1 more source