Results 61 to 70 of about 4,879,388 (250)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Creating a Computing Programs Package to Aid in the Assessment and Prognosis of Patients Suffering from Cerebrovascular Diseases

Medisur, 2007
Fundament: The have an evaluation and prognosis of patients suffering from cerebrovascular diseases in its acute phase is important in order to define the medical management as well as others several aspects.
Carlos Jaime Geroy Gómez, Rubén Bembibre Taboada, Darian Alvarez Rodriguez, Miguel Angel Buergo Zuaznábar, Diosdania Alfonso Falcón   +4 more
doaj  

Software livre de produção textual com predição de palavras: um aliado do aluno especial Text production with a word predicition free-ware software: support for the special student

Revista Brasileira de Educação Especial, 2009
A dificuldade em comunicar-se naturalmente, seja através da fala ou da escrita, pode fazer com que uma pessoa seja impedida de demonstrar e desenvolver seus potenciais cognitivos, sociais e criativos. Essa realidade tem sido amplamente estudada, buscando
Monica Jordan, Percy Nohama, Alceu de Souza Britto Júnior   +2 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Characterization of security defects and analysis of vulnerability criticality in software for automated systems of internal affairs bodies

Вестник Дагестанского государственного технического университета: Технические науки
Objective. The purpose of the study is to theoretically analyze security defects and study the criticality of vulnerabilities in software used in modern automated systems of internal affairs agencies.Method.
I. G. Drovnikova, A. D. Popova
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Heron, a Knowledge Graph editor for intuitive implementation of Python-based experimental pipelines

eLife
To realise a research project, experimenters face conflicting design and implementation choices across hardware and software. These include balancing ease of implementation – time, expertise, and resources – against future flexibility, the number of ...
George Dimitriadis, Ella Svahn, Andrew F MacAskill, Athena Akrami   +3 more
doaj   +1 more source

Alfabetización científica y tecnológica en las instituciones educativas de básica y media y el desarrollo de pensamiento crítico, lógico y matemático como factor generador de una industria de software en Colombia

CITAS, 2018
Este proyecto de investigación reconoce la importancia de identificar, caracterizar los procesos de formación en el área de Tecnología e Informática y el nivel de desarrollo del pensamiento crítico y lógico matemático que suscita en los estudiantes de ...
Floralba Gómez Castaño, Mario Contreras Castro, Pastor Martín Bohórquez, Yadira Ruiz Díaz   +3 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

PROGRAM GOALS MANAGEMENT OF THE ENTITIES: OPPORTUNITIES AND PROSPECTS OF ADAPTATION TO CONDITIONS OF THE TRANSITIONAL ECONOMY

Модернизация, инновация, развитие, 2015
The subject / topic. The relevance of this study is due to the fact that the current strategic goal of Economic Development is to create conditions that will ensure high and stable economic growth of the country and its socio-economic systems. One of the
Vitalii A. Vernikov
doaj   +1 more source