Results 111 to 120 of about 7,116,394 (358)

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

Molecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou, Argyro Roumeliotou, Evangelia Pantazaka, Athanasios‐Nasir Shaukat, Athina Christopoulou, Angelos Koutras, Foteinos‐Ioannis Dimitrakopoulos, Vassilis Georgoulias, Anastasia Xagara, Evangelia Chantzara, Fillipos Koinis, Athanasios Kotsakis, Constantinos Stathopoulos, Galatea Kallergi   +13 more
wiley   +1 more source

OpenSim: Open-Source Software to Create and Analyze Dynamic Simulations of Movement

IEEE Transactions on Biomedical Engineering, 2007
Dynamic simulations of movement allow one to study neuromuscular coordination, analyze athletic performance, and estimate internal loading of the musculoskeletal system.
S. Delp, F. Anderson, A. Arnold, P. Loan, Ayman Habib, Chand T. John, Eran Guendelman, D. Thelen   +7 more
semanticscholar   +1 more source

New tools for automated high-resolution cryo-EM structure determination in RELION-3

eLife, 2018
Here, we describe the third major release of RELION. CPU-based vector acceleration has been added in addition to GPU support, which provides flexibility in use of resources and avoids memory limitations.
Jasenko Zivanov, Takanori Nakane, Björn O Forsberg, Dari Kimanius, Wim JH Hagen, Erik Lindahl, Sjors HW Scheres   +6 more
doaj   +1 more source

Free software, Open source software, licenses. A short presentation including a procedure for research software and data dissemination [PDF]

arXiv, 2014
The main goal of this document is to help the research community to understand the basic concepts of software distribution: Free software, Open source software, licenses. This document also includes a procedure for research software and data dissemination.
arxiv  

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

Molecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang, Ting Guo, Xiaofang Xing, Xijuan Liu, Xuejun Gan, Yingai Li, Yan Liu, Fei Shan, Zhouqiao Wu, Jiafu Ji, Ziyu Li   +10 more
wiley   +1 more source

Relative expression software tool (REST©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR

, 2002
Real-time reverse transcription followed by polymerase chain reaction (RT–PCR) is the most suitable method for the detection and quantification of mRNA. It offers high sensitivity, good reproducibility and a wide quantification range.
M. Pfaffl, G. Horgan, L. Dempfle
semanticscholar   +1 more source

On the naturalness of software

Communications of the ACM, 2012
Natural languages like English are rich, complex, and powerful. The highly creative and graceful use of languages like English and Tamil, by masters like Shakespeare and Avvaiyar, can certainly delight and inspire. But in practice, given cognitive constraints and the exigencies of daily life, most human utterances are far simpler and much more ...
Hindle, Abram, Barr, E.T., Su, Z., Devanbu, P.T., Gabel, M.   +4 more
openaire   +6 more sources

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

Molecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park, Sang Shin Lee, Shihyun Kim, Yeonjun Lee, Gyeonwon Park, Jung Oh Kim, Jongho Choi   +6 more
wiley   +1 more source

Trampas cámara como herramienta para estudiar mamíferos silvestres

Mammalogy Notes, 2018
Como muchos biólogos interesados en monitorear o estudiar mamíferos medianos y grandes, en estado silvestre, me he enfrentado a las clásicas preguntas como: ¿Cuántas cámaras necesito?, ¿Qué cámara compramos?, ¿Cómo las instalo? ¿Qué protocolos sigo?
Diego J. Lizcano
doaj   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source