Results 111 to 120 of about 12,672,734 (314)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Crashed Software: Assessing Product Liability for Software Defects in Automated Vehicles [PDF]

open access: yes, 2018
Automated vehicles will not only redefine the role of drivers, but also present new challenges in assessing product liability. In light of the increased risks of software defects in automated vehicles, this Note will review the current legal and ...
Kim, Sunghyo
core   +1 more source

Software and Software Engineering

open access: yes, 2020
Software Komputer atau Perangkat Lunak Komputer merupakan merupakan produk atau aplikasi yang dibuat secara profesional dan jangka panjang. Didalamnya meliputi program yang dapat dieksekusi oleh komputer yang terdiri dari beberapa arsitektur dan konten serta sejumlah informasi.
openaire   +2 more sources

UAV Mission Computer Operation Mode Optimization Focusing on Computational Energy Efficiency and System Responsiveness

open access: yesComputation
The rising popularity of UAVs and other autonomous control systems coupled with real-time operating systems has increased the complexity of developing systems with the proper robustness, performance, and reactivity.
Oleksandr Liubimov   +3 more
doaj   +1 more source

DEVELOPMENT OF SOFTWARE FOR EVALUATION OF DEFECT-FREE MANUFACTURE OF BAKERY PRODUCTS [PDF]

open access: yesТехника и технология пищевых производств, 2015
In the process of production, it is necessary to control the quality and safety of products. In addition, each manufacturer determines his way of control.
Beznosov Y.V.   +2 more
doaj  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Evaluation of software dependability [PDF]

open access: yes, 1996
It has been said that the term software engineering is an aspiration not a description. We would like to be able to claim that we engineer software, in the same sense that we engineer an aero-engine, but most of us would agree that this is not currently ...
Littlewood, B.
core  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Modern Tanscriptome Data Rrocessing Algorithms: a Review of Methods and Results of Approbation

open access: yesЦифровая трансформация, 2021
Analysis of bioinformatics data is an actual problem in modern computational biology and applied mathematics. With the development of biotechnology, as well as tools for obtaining and processing information derived from biological objects and systems ...
M. V. Sprindzuk   +3 more
doaj  

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