Results 31 to 40 of about 541,753 (313)
Software Architecture Degradation in Open Source Software: A Systematic Literature Review
Software architecture (SA) has a prominent role in all stages of system development. Given the persistent evolution of software systems over time, SA tends to be eroded or degraded. Such phenomenon is called architectural degradation.
Ahmed Baabad +3 more
doaj +1 more source
Architecture principles affect a software system holistically. Given their alignment with a business strategy, they should be incorporated within the validation process covering aspects of sustainability. However, current research discusses the influence
Markus Funke +3 more
doaj +1 more source
An active-architecture approach to COTS integration
Commercial off-the-shelf (COTS) software products are increasingly used as standard components within integrated information systems. This creates challenges since both their developers and source code are not usually available, and the ongoing ...
Balasubramaniam, Dharini +8 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
There are three different well-known methods for predicting the manoeuvrability of ships: (1) free running model test, (2) direct manoeuvring simulation using CFD and (3) system-based manoeuvring simulation.
In-Tae Kim +7 more
doaj +1 more source
Software architecture visualisation [PDF]
Tracing the history of software engineering reveals a series of abstractions. In early days, software engineers would construct software using machine code.
Hatch, Andrew
core
Dominion : an architecture-driven approach to generating efficient constraint solvers
This work is supported by the EPSRC grant “A Constraint Solver Synthesiser” (EP/H004092/1) and SICSA studentships.Constraints are used to solve combinatorial problems in a variety of industrial and academic disciplines.
Balasubramaniam, Dharini +11 more
core +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
This study addresses the prevalent gap between structured models and informal architectural methodologies in software engineering. Recognizing the potential of informal architecture artifacts in analytical processes, we introduce a methodology that ...
Joshua Kaplan, Luis Rabelo
doaj +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source

