Results 41 to 50 of about 5,174,549 (302)
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Towards Software Architecture as an Auditable Practice
Applied SciencesA system’s architectural design plays a vital role in its quality, since quality attributes are system-wide and impacted by the architecture. The evaluation of a software architecture aims to assess its suitability for the purpose of the system, making ...
Pablo Cruz +2 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Software-Defined Metaverse (SDM) Architecture
Journal of MetaverseThe metaverse, a vast virtual shared space that integrates enhanced physical reality with persistent virtual environments, has the potential to revolutionize digital interaction by providing deeply immersive and interactive experiences.
Ahmed Shalaby +2 more
doaj +1 more source
International Journal of Information Systems and Project Management, 2013 The concept of Information Systems urbanization has been proposed since the late 1990’s in order to help organizations building agile information systems.
Sana Guetat, Salem Dakhli, , ,
doaj +1 more source
International Journal of Naval Architecture and Ocean Engineering, 2021 There are three different well-known methods for predicting the manoeuvrability of ships: (1) free running model test, (2) direct manoeuvring simulation using CFD and (3) system-based manoeuvring simulation.
In-Tae Kim +7 more
doaj +1 more source
Software Architecture For Product Lines
, 2014 Software product lines were designed from the product line tested out by H. Ford at the beginning of the 20 the Century, which led to the success of his automotive production.
Arboleda Jiménez, Hugo Fernando
core +1 more source
An active-architecture approach to COTS integration [PDF]
, 2005 Commercial off-the-shelf (COTS) software products are increasingly used as standard components within integrated information systems. This creates challenges since both their developers and source code are not usually available, and the ongoing ...
Balasubramaniam, Dharini +16 more
core +1 more source
, 2022 S.234-238Software architecture has been proven as a conceptual tool to manage the development and evolution of a software product. However, integrating architecting as an activity in software engineering is still perceived as a major challenge in ...
Naab, Matthias +3 more
core +1 more source