Results 71 to 80 of about 704,237 (259)

Metodología para la selección de sistemas enterprise resource planning desplegados en la nube para pequeñas y medianas empresas: Aproximación alineada con la realidad ecuatoriana

open access: yesMaskana, 2017
En la actualidad los Sistemas de Planeación de Recursos Empresariales (Enterprise Resource Planning; ERP) representan una herramienta esencial para las empresas que buscan la automatización de sus procesos, de ahí que varias compañías empleen mucho ...
Fabián Carrión, Priscila Cedillo
doaj  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Technological development trends: Application service model (ASP) or 'Cloud Computing' [PDF]

open access: yesAnali Ekonomskog fakulteta u Subotici, 2014
The paper discusses modern technological approaches and Internet concepts that are significantly and rapidly changing the view of the global business world.
Trninić Jelica, Đurković Jovica
doaj  

A Systematic Mapping Study of MMOG Backend Architectures

open access: yesInformation, 2019
The advent of utility computing has revolutionized almost every sector of traditionalsoftware development. Especially commercial cloud computing services, pioneered by the likesof Amazon, Google and Microsoft, have provided an unprecedented opportunity ...
Nearchos Paspallis, Nicos Kasenides
doaj   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano   +11 more
wiley   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall   +16 more
wiley   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown   +6 more
wiley   +1 more source

Sourcing Lifecycle for Software as a Service (SAAS)

open access: yesEPJ Web of Conferences, 2014
In recent years, Software as a Service (SaaS) has changed from curiosity caused concept to an accepted well known concept. A key advantage of this model is that, by cautious engineering, it is possible to influence economy of scale to decrease total cost
Santy , Sikkel K.
doaj   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

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