Results 91 to 100 of about 2,092,569 (323)

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Enhancing bending performance of cemented lithium feldspar tailings backfill with 3D printing polymer lattices: Effects of unit shapes and materials

open access: yesCase Studies in Construction Materials
To comprehensively test and analyze the effects of three-dimensional printed polymer lattice (3DPPL) on the bending performance of cemented lithium feldspar tailings backfill (CLFTB) specimens, this study conducted three-point bending test on 3DPPL ...
Ling Hu   +4 more
doaj   +1 more source

A Framework for Evaluating Model-Driven Self-adaptive Software Systems [PDF]

open access: yes, 2019
In the last few years, Model Driven Development (MDD), Component-based Software Development (CBSD), and context-oriented software have become interesting alternatives for the design and construction of self-adaptive software systems.
Magableh, Basel
core   +2 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

The method of using current regulations and standards in designing management and technologies of construction

open access: yesMATEC Web of Conferences, 2017
Economic efficiency of using funds in construction of buildings and structures begins from an effective, proper design, which is based on modern, cutting-edge, advanced equipment, streamlined organization and process solutions of construction operations.
Sinenko Sergey
doaj   +1 more source

Mathematical modeling of irrigation canal systems. Part I - Presentation of the "Mistral-Simutra" software package; Part II - Application of "Mistral - Simutra" to the Kalankuttiya branch canal (Mahaweli System H) Sri Lanka [PDF]

open access: yes
Mathematical models / Computer software / Canal construction / Simulation models / Sri Lanka / Mahaweli Project ...
Arumugam, J., Berthery, D., Sally, H.
core  

EbbRT: Elastic Building Block Runtime - overview [PDF]

open access: yes, 2015
EbbRT provides a lightweight runtime that enables the construction of reusable, low-level system software which can integrate with existing, general purpose systems. It achieves this by providing a library that can be linked into a process on an existing
Appavoo, Jonathan   +4 more
core   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

A systematic approach for component-based software development [PDF]

open access: yes, 2000
Component-based software development enables the construction of software artefacts by assembling prefabricated, configurable and independently evolving building blocks, called software components.
Ferreira Pires, L.   +2 more
core   +3 more sources

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