Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Molecular Oncology, EarlyView.Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson +11 more
wiley +1 more source
MATEC Web of Conferences, 2017 Economic efficiency of using funds in construction of buildings and structures begins from an effective, proper design, which is based on modern, cutting-edge, advanced equipment, streamlined organization and process solutions of construction operations.
Sinenko Sergey
doaj +1 more source
Mathematical modeling of irrigation canal systems. Part I - Presentation of the "Mistral-Simutra" software package; Part II - Application of "Mistral - Simutra" to the Kalankuttiya branch canal (Mahaweli System H) Sri Lanka [PDF]
Mathematical models / Computer software / Canal construction / Simulation models / Sri Lanka / Mahaweli Project ...
Arumugam, J., Berthery, D., Sally, H.
core
Molecular Oncology, EarlyView.Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu +11 more
wiley +1 more source
EbbRT: Elastic Building Block Runtime - overview [PDF]
, 2015 EbbRT provides a lightweight runtime that enables the construction of reusable, low-level system software which can integrate with existing, general purpose systems. It achieves this by providing a library that can be linked into a process on an existing
Appavoo, Jonathan +4 more
core +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
البرمجيات الحـــــديثة في المســــــــــح الكــــــمي للمشــــــــــــاريع الإنشــــــــــــــائية
Journal of Engineering and Sustainable Development, 2014 The engineering project management is one of the most important elements contributing to the success or failure of a business, there is no doubt about how important is the management to succeed in any area, especially in the field of construction ...
محمد مصــلح سلــمان +1 more
doaj
A Framework for Evaluating Model-Driven Self-adaptive Software Systems [PDF]
, 2019 In the last few years, Model Driven Development (MDD), Component-based Software Development (CBSD), and context-oriented software have become interesting alternatives for the design and construction of self-adaptive software systems.
Magableh, Basel
core +2 more sources
Software engineering or methods for the multi-person construction of multi-version programs [PDF]
, 1975 David Lorge Parnas
openalex +1 more source
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source