Results 131 to 140 of about 2,092,569 (323)
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
DivNEDS: Diverse Naturalistic Edge Driving Scene Dataset for Autonomous Vehicle Scene Understanding
The safe implementation and adoption of Autonomous Vehicle (AV) vision models on public roads requires not only an understanding of the natural environment comprising pedestrians and other vehicles but also the ability to reason about edge situations ...
John Owusu Duah +2 more
doaj +1 more source
Automated Construction of Node Software Using Attributes in a Ubiquitous Sensor Network Environment [PDF]
Woojin Lee, Juil Kim, Jang-Mook Kang
openalex +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
A comparison testing of software products for road pavements construction calculation [PDF]
Alexander A. Neretin +1 more
openalex +1 more source
A project to investigate mechanisms and methodologies for the design and construction of communicating concurrent processes in real-time environments [PDF]
Research undertaken in 1979 into effective and appropriate mechanisms to aid in the design and construction of software for use in the flight research programs undertaken by NASA is ...
Campbell, R. H., Horton, K.
core +1 more source
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Construction and Development of Software Platform for Wind-related Researches of High-rise Building [PDF]
Pei Hu, Yong Quan
openalex +1 more source
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga +8 more
wiley +1 more source

