Results 51 to 60 of about 8,323,849 (282)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Traffic Engineering in Software Defined Networks: A Survey
Journal of Telecommunications and Information Technology, 2016 An important technique to optimize a network and improve network robustness is traffic engineering. As traffic demand increases, traffic engineering can reduce service degradation and failure in the network. To allow a network to adapt to changes in the
Mohammad Reza Abbasi +2 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Development Prospects of Software Defined Optical Networks
Dianxin kexue, 2014 In order to meet the requirement of continued growth in broadband services and applications, optical networks need to be more and more flexible and controllable.
Yuefeng Ji, Jie Zhang, Yongli Zhao
doaj +2 more sources
Towards Causal Consistent Updates in Software-Defined Networks
Applied Sciences, 2020 A network paradigm called the Software-Defined Network (SDN) has recently been introduced. The idea of SDN is to separate the control logic from forwarding devices to enable a centralized control platform.
Amine Guidara +4 more
doaj +1 more source
Software defined intelligent satellite-terrestrial integrated networks: Insights and challenges
Digital Communications and Networks, 2023 Satellite-Terrestrial integrated Networks (STNs) have been advocated by both academia and industry as a promising network paradigm to achieve service continuity and ubiquity.
Shuo Yuan +3 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
On the Update Problems for Software Defined Networks
Моделирование и анализ информационных систем, 2014 The designing of network update algorithms is urgent for the development of SDN control software. A particular case of Network Update Problem is that of restoring seamlessly a given network configuration after some packet forwarding rules have been ...
V. A. Zakharov, E. V. Chemeritsky
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Organization of Multi-controller Interaction in Software Defined Networks
Моделирование и анализ информационных систем, 2018 Software Defined Networking (SDN) is a promising paradigm for network management. It is a centralized network intelligence on a dedicated server, which runs network operating system, and is called SDN controller.
Sergey V. Morzhov +2 more
doaj +1 more source