Results 61 to 70 of about 8,323,849 (282)

Monitoring Jitter in Software Defined Networks

, 2022
End-to-end jitter of a flow is an important metric that indicates the Quality of Service a user is experiencing, particularly for real-time applications such as video streaming, cloud gaming, and so on. Monitoring the jitter can help controllers make routing decisions for certain flows.
Jithin Kallukalam Sojan, K. Haribabu 0001   +1 more
openaire   +3 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

5G Networks Based on Software Defined Network

Iraqi Journal of Information & Communication Technology
A software-defined network (SDN) based 5G architecture that utilizes three controllers to improve network performance is proposed in this paper. The controllers are responsible for managing functions related to access mechanism, core connectivity ...
Noor I. Khalaf, Abdulkareem A. Kadhim
doaj   +1 more source

Efficient topology discovery algorithm for software‐defined networks

IET Networks, 2017
Software‐defined networking (SDN) already has an established presence in the networking industry as an emerging paradigm for designing network architectures, decoupling the control from the forwarding plane and offering a centralised way of network ...
George Tarnaras, Fanouria Athanasiou, Spyros Denazis   +2 more
doaj   +1 more source

Fault-Tolerance Distributed Control Plane for Software Defined Networks

Моделирование и анализ информационных систем, 2019
The architecture of the high availability distributed control plane for SDN/OpenFlow networks are considered. High availability is achieved by redundancy of controller instances, active switch-controller communications, computing resources and tools for ...
Vasily N. Pashkov
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

The (In)Security of Virtualization in Software Defined Networks

IEEE Access, 2019
Software Defined Networking (SDN) is a new networking paradigm with the promise to increase simplicity and efficiency in network management through the separation of control functions from the forwarding functions.
Talal Alharbi, Marius Portmann
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

A Hybrid Routing Protocol for Wireless Distributed Networks

IEEE Access, 2018
Trends in networking are shifting from distributed to logically centralized networks. Software defined networking (SDN) is the key technology behind this shift.
Malik Najmus Siraj, Zaheer Ahmed, Muhammad Kashif Hanif, Muhammad Hasanain Chaudary, Shoab Ahmed Khan, Nadeem Javaid   +5 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source