Results 141 to 150 of about 21,707,590 (377)

Multimodal Minimal-Angular-Geometry Representation for Real-Time Dynamic Mexican Sign Language Recognition

open access: yesTechnologies
Current approaches to dynamic sign language recognition commonly rely on dense landmark representations, which impose high computational cost and hinder real-time deployment on resource-constrained devices.
Gerardo Garcia-Gil   +2 more
doaj   +1 more source

The design of an integrated support software system [PDF]

open access: bronze, 1982
Arra S. Avakian   +2 more
openalex   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Human-Machine Interaction: A Vision-Based Approach for Controlling a Robotic Hand Through Human Hand Movements

open access: yesTechnologies
An anthropomorphic robot is a mechanical device designed to perform human-like tasks, such as manipulating objects, and has been one of the significant contributions in robotics over the past 60 years.
Gerardo García-Gil   +2 more
doaj   +1 more source

Microcomputer software design

open access: yesProceedings of the May 19-22, 1975, national computer conference and exposition on - AFIPS '75, 1975
The general availability of low cost microcomputers has revolutionized digital design and digital applications. Using LSI chip technology, microcomputers are no more than scaled-down central processing units with minicomputer capability, and are treated as component computers at the heart of a digital design.
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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