Results 121 to 130 of about 14,237,440 (297)
Shiyou jixie, 2020 The researches on the drainage and gas recovery technology of concentric dual-tubing jet pump mainly focus on the structural design of the jet pump core, or a brief introduction to the production process of jet pump.
Yu Jiaojiao +5 more
doaj
A Fully Collaborative, Noteless Electronic Medical Record Designed to Minimize Information Chaos: Software Design and Feasibility Study. [PDF]
JMIR Form Res, 2021 Steinkamp J +3 more
europepmc +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Data Comparison and Software Design for Easy Selection and Application of CRISPR-based Genome Editing Systems in Plants. [PDF]
Genomics Proteomics Bioinformatics, 2021 Wang Y +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
The Program Principle and Application of Microscopic Identification of Minerals
Yankuang ceshi, 2013 The microscopic identification of minerals can often be improved with the use of computer technology. An auxiliary analysis program for the microscopic identification of minerals based on Visual Basic tools is described in this paper.
WANG Lu-xin, FANG Qing-hua, WU Chao-dong
doaj
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Mobile application for coordinating volunteer processes
Технічна інженеріяModern information technologies play a key role in the development of social initiatives, in particular in the field of volunteering. Mobile applications are becoming an effective tool for organizing communication, coordinating actions and providing ...
I.M. Sakhatska +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source