Results 101 to 110 of about 22,627,137 (391)

Agile Research [PDF]

open access: yesarXiv, 2012
This paper discusses the application of agile software development methods in software-based research environments.
arxiv  

MANAi -- An IntelliJ Plugin for Software Energy Consumption Profiling [PDF]

open access: yesarXiv, 2022
Developing energy-efficient software solutions is a tedious task. We need both, the awareness that energy-efficiency plays a key role in modern software development and the tools and techniques to support stakeholders involved in the software development lifecycle.
arxiv  

Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment

open access: yesFEBS Letters, Volume 599, Issue 7, Page 1006-1028, April 2025.
This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause   +2 more
wiley   +1 more source

BioRel: towards large-scale biomedical relation extraction

open access: yesBMC Bioinformatics, 2020
Background Although biomedical publications and literature are growing rapidly, there still lacks structured knowledge that can be easily processed by computer programs.
Rui Xing, Jie Luo, Tengwei Song
doaj   +1 more source

Why developers cannot embed privacy into software systems? An empirical investigation [PDF]

open access: yes22nd International Conference on Evaluation and Assessment in Software Engineering, 2018, 2018
Pervasive use of software applications continues to challenge user privacy when users interact with software systems. Even though privacy practices such as Privacy by Design (PbD), have clear in- structions for software developers to embed privacy into software designs, those practices are yet to become a common practice among software developers.
arxiv  

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

Behavior Modeling on ARINC653 to Support the Temporal Verification of Conformed Application Design

open access: yesIEEE Access, 2019
Numerous factors have an impact on the temporal correction of integrated modular avionics application. As early as in the design phase, verification should be conducted to guarantee the rigorous temporal requirements for safety consideration which are ...
Kui Zhang   +4 more
doaj   +1 more source

Cleanroom software development [PDF]

open access: yes
The 'cleanroom' software development process is a technical and organizational approach to developing software with certifiable reliability. Key ideas behind the process are well structured software specifications, randomized testing methods and the ...
Dyer, M., Mills, H. D.
core   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

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