Results 111 to 120 of about 3,419,394 (318)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
GTRF: A Game Theory Approach for Regulating Node Behavior in Real-Time Wireless Sensor Networks
Sensors, 2015 The selfish behaviors of nodes (or selfish nodes) cause packet loss, network congestion or even void regions in real-time wireless sensor networks, which greatly decrease the network performance.
Chi Lin, Guowei Wu, Poria Pirozmand
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Reconfigurability Function Deployment in Software Development [PDF]
In the forthcoming highly dynamic and complex business environment high-speed and cost-effective development of software applications for targeting a precise, unique and momentary set of requirements (no more-no less) associated to a customized business ...
Emilia BRAD +4 more
core
Learning Irregular Space Transformation for Person Re-Identification
IEEE Access, 2018 Person re-identification (ReID) classifies the discriminative features of different people. Human perception usually depends on the minority of discriminative colors to classify targets, rather than the majority of mutual colors. ReID uses a small number
Yanwei Zheng +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Software Engineering Technology A Web Repository of Lessons Learned from
, 2008 The development of commercial offthe-shelf (COTS)-based software is different in many respects from in-house software development. Since COTS requires different activities and skills, we need to build a body of knowledge about COTSbased software ...
Cots-based Software Development
core
Maturity of Software Modelling and Model Driven Engineering: a Survey in the Italian Industry [PDF]
, 2012 Background: The main claimed advantage of Model-driven engineering is improvement in productivity. However, few information is available about its actual adoption during software development and maintenance in the industry.
Tiso, Alessandro +14 more
core +1 more source
Effects of Sensor Location on Dynamic Load Estimation in Weigh-in-Motion System
Sensors, 2018 In recent years, weigh-in-motion systems based on embedded sensor networks have received a lot of attention. However, how to improve the accuracy of multi-sensor weigh-in-motion (WIM) systems while keeping costs low remains a challenge.
Tianhao Qin +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source