Results 41 to 50 of about 2,881,506 (238)
Human-Machine Hybrid Peer Grading in SPOCs
IEEE Access, 2020 Peer grading, allowing students/peers to evaluate others' assignments, offers a promising solution for scaling evaluation and learning to massive open online courses (MOOCs) and small private online courses (SPOCs).
Yong Han +3 more
doaj +1 more source
uDMA: An Efficient User-Level DMA for NVMe SSDs
Applied Sciences, 2023 The Non-Volatile Memory Express (NVMe) SSD provides high I/O performance for current computer systems, and direct memory access (DMA) is the critical enabling mechanism for direct I/O. However, the lengthy I/O stack becomes a new bottleneck that degrades
Jinbin Zhu +3 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Algorithms, 2020 In recent years, a forward-looking subfield of machine learning has emerged with important applications in a variety of scientific fields. Semi-supervised learning is increasingly being recognized as a burgeoning area embracing a plethora of efficient ...
Stamatis Karlos +2 more
doaj +1 more source
Expert Survey on Current Trends in Agile, Disciplined and Hybrid Practices for Software Development
Applied Computer Systems, 2021 Every software development company makes software development based on a specific approach. There are a number of approaches to software development, both disciplined and agile. Each approach includes a set of different activities.
Ņikiforova Oksana +2 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Developer Assignment Method for Software Defects Based on Related Issue Prediction
MathematicsThe open-source software platform hosts a large number of software defects, and the task of relying on administrators to manually assign developers is often time consuming.
Baochuan Liu +3 more
doaj +1 more source