Results 41 to 50 of about 7,103,185 (329)
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
The evaluation of risk and uncertainty in the context of software project management is the subject of this paper. This paper discusses the difficulties faced by project managers in handling uncertainty brought on by the complex nature of software ...
Anastasiia Strielkina +2 more
doaj +1 more source
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
COW-IMM: A Novel Integrity Measurement Method Based on Copy-on-Write for File in Virtual Machine
The integrity measurement method is used to detect whether the files are tampered with and to build a trusted environment. It can improve the security of virtual machines using base and increment image.
Shupan Li +4 more
doaj +1 more source
Human-Machine Hybrid Peer Grading in SPOCs
Peer grading, allowing students/peers to evaluate others' assignments, offers a promising solution for scaling evaluation and learning to massive open online courses (MOOCs) and small private online courses (SPOCs).
Yong Han +3 more
doaj +1 more source
uDMA: An Efficient User-Level DMA for NVMe SSDs
The Non-Volatile Memory Express (NVMe) SSD provides high I/O performance for current computer systems, and direct memory access (DMA) is the critical enabling mechanism for direct I/O. However, the lengthy I/O stack becomes a new bottleneck that degrades
Jinbin Zhu +3 more
doaj +1 more source
Development of a Modular Software Architecture for Underwater Vehicles Using Systems Engineering [PDF]
Carlos A. Zuluaga +5 more
openalex +1 more source
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii +8 more
wiley +1 more source
Mitochondrial fatty acid oxidation is stimulated by red light irradiation
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera +4 more
wiley +1 more source

