Results 61 to 70 of about 20,143,612 (313)
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Developing Scientific Software [PDF]
Not all scientific computing is high-performance computing—the variety of scientific software is huge. Such software might be complex simulation software developed and running on a high-performance computer, or software developed on a PC for embedding into instruments; for manipulating, analyzing or visualizing data or for orchestrating workflows. This
Judith Segal, Chris Morris
openaire +2 more sources
The evaluation of risk and uncertainty in the context of software project management is the subject of this paper. This paper discusses the difficulties faced by project managers in handling uncertainty brought on by the complex nature of software ...
Anastasiia Strielkina +2 more
doaj +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
An Investigation into Software Estimation Methods [PDF]
There are currently no fully validated estimation approaches that can accurately predict the effort needed for developing a software system (Kitchenham, et al, 1995).
Hamdan, Khaled
core +5 more sources
COW-IMM: A Novel Integrity Measurement Method Based on Copy-on-Write for File in Virtual Machine
The integrity measurement method is used to detect whether the files are tampered with and to build a trusted environment. It can improve the security of virtual machines using base and increment image.
Shupan Li +4 more
doaj +1 more source
Human-Machine Hybrid Peer Grading in SPOCs
Peer grading, allowing students/peers to evaluate others' assignments, offers a promising solution for scaling evaluation and learning to massive open online courses (MOOCs) and small private online courses (SPOCs).
Yong Han +3 more
doaj +1 more source
uDMA: An Efficient User-Level DMA for NVMe SSDs
The Non-Volatile Memory Express (NVMe) SSD provides high I/O performance for current computer systems, and direct memory access (DMA) is the critical enabling mechanism for direct I/O. However, the lengthy I/O stack becomes a new bottleneck that degrades
Jinbin Zhu +3 more
doaj +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source

