Results 71 to 80 of about 4,371,078 (240)

Cleanroom software development [PDF]

open access: yes
The 'cleanroom' software development process is a technical and organizational approach to developing software with certifiable reliability. Key ideas behind the process are well structured software specifications, randomized testing methods and the ...
Dyer, M., Mills, H. D.
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Automated software development workstation [PDF]

open access: yes
Engineering software development was automated using an expert system (rule-based) approach. The use of this technology offers benefits not available from current software development and maintenance methodologies.

core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

BioRel: towards large-scale biomedical relation extraction

open access: yesBMC Bioinformatics, 2020
Background Although biomedical publications and literature are growing rapidly, there still lacks structured knowledge that can be easily processed by computer programs.
Rui Xing, Jie Luo, Tengwei Song
doaj   +1 more source

Software development: Stratosphere modeling [PDF]

open access: yes
A more comprehensive model for stratospheric chemistry and transport theory was developed for the purpose of aiding predictions of changes in the stratospheric ozone content as a consequence of natural and anthropogenic processes.
Chen, H. C.
core   +1 more source

Value stream mapping for software development process [PDF]

open access: yes, 2004
Includes bibliographical ...
Thummala, Ganesh S.
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Machine learning model for predicting cyber-criminal characteristics

open access: yesKuwait Journal of Science
This study aims to predict investigation outcomes of individual cybercrime cases using the most relevant information provided by complainants. We curated a dataset on solved hacking cases from 2019 to 2022 from the cyber-crime combating department (3CD ...
Hesham A. Almansouri   +2 more
doaj   +1 more source

Teaching Software Development to Non-Software Engineering Students [PDF]

open access: yes
This paper argues that although the object-oriented programming (OOP) paradigm is appropriate for students taking programming modules on Higher Education (HE) software engineering course, this paradigm is not as relevant for students from other courses ...
Colvin, John
core  

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