Results 51 to 60 of about 4,371,078 (240)
Enabling Multi-Stakeholder Cooperative Modelling in Automotive Software Development and Implications for Model Driven Software Development [PDF]
, 2008 One of the motivations for a model driven approach to software development is to increase the involvement for a range of stakeholders in the requirements phases.
Grimm, F. +2 more
core
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Algorithms, 2020 In recent years, a forward-looking subfield of machine learning has emerged with important applications in a variety of scientific fields. Semi-supervised learning is increasingly being recognized as a burgeoning area embracing a plethora of efficient ...
Stamatis Karlos +2 more
doaj +1 more source
Exploring collaboration patterns among global software development teams. [PDF]
, 2009 This study examines communication behaviors in global software student teams. The authors of the paper characterize the types of communication behaviors that occur when student teams are engaged in a software development project. The authors present
Alpaslan, Ferda Nur +6 more
core +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Developer Assignment Method for Software Defects Based on Related Issue Prediction
MathematicsThe open-source software platform hosts a large number of software defects, and the task of relying on administrators to manually assign developers is often time consuming.
Baochuan Liu +3 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The Dynamics of Creativity in Software Development
, 2013 Software is primarily developed for people by people and human factors must be studied in all software engineering phases. Creativity is the source to improvise solutions to problems for dominating complex systems such as software development.
Graziotin, Daniel
core +2 more sources