Results 71 to 80 of about 25,098,289 (293)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

DATABASE DEVELOPMENT LIFE CYCLE [PDF]

open access: yes
A software development life cycle model (SDLC) consists of a set of processes (planning, requirements, design, development, testing, installation and maintenance) defined to accomplish the task of developing a software application that is functionally ...
Morgan D. Monger   +2 more
core  

An Investigation into Software Estimation Methods [PDF]

open access: yes
There are currently no fully validated estimation approaches that can accurately predict the effort needed for developing a software system (Kitchenham, et al, 1995).
Hamdan, Khaled
core   +6 more sources

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Modelling Quantum Software

open access: yesMemoria Investigaciones en Ingeniería
This annotated bibliography delves into the field of quantum computing, focusing specifically on the resources used throughout the software life cycle.
Luis Mariano Bibbo   +3 more
doaj   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

Redefining life cycle for a building sustainability assessment framework [PDF]

open access: yes, 2005
Understanding the differences between the temporal and physical aspects of the building life\ud cycle is an essential ingredient in the development of Building Environmental Assessment\ud (BEA) tools.
Watson, Phillipa, Jones, Delwyn
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Secure Software Development Life Cycle Processes: A Technology Scouting Report

open access: yes, 2018
As the use of the Internet and networked systems become more pervasive, the importance of developing secure software increases. The purpose of this technical note is to present overview information about existing processes, standards, life cycle models ...
Noopur Davis (5407151)
core   +1 more source

Decision Support System for Choosing a Model for a Software Development Life Cycle

open access: yesOperations Research and Decisions, 2010
The aim of this paper is to present selected models of a Software Development Life Cycle as a set of possible alternatives. The article also includes the characteristics of IT projects which are used as the basis for selection criteria, according to ...
Grażyna Hołodnik-Janczura   +1 more
doaj  

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