Results 81 to 90 of about 25,098,289 (293)

PERENCANAAN PENGEMBANGAN ARSITEKTUR SISTEM INFORMASI PERGURUAN TINGGI MENGGUNAKAN METODE ENTERPRISE UNIFIED PROCESS (EUP) (STUDI KASUS : STMIK CIC CIREBON)

SINTECH (Science and Information Technology) Journal, 2018
Enterprise Unified Process (EUP) as one of the methods or terms of reference for building an information architecture is a development cycle of Information Technology (IT) extension of the Rational Unified Process (RUP).
Petrus Sokibi, I Ketut Widhi Adnyana
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

State of the Software Development Life-Cycle for the Internet-of-Things

CoRR, 2018
38 ...
João Pedro Dias, Hugo Sereno Ferreira
openaire   +3 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

DEFINITION AND FORMALIZATION OF THE SOFTWARE FUNCTIONAL STATE CONCEPT THROUGHOUT THE DEVELOPMENT LIFE CYCLE

Електроніка та інформаційні технології
Background. Today, software is a critically important component of any information system. Its development requires significant resources and complex technical solutions, and the development of technologies is so rapid that not all concepts and ...
Mariia Lyashkevych, Vasyl Lyashkevych, Roman Shuvar   +2 more
doaj   +1 more source

Active Internationalization of Small and Medium-Sized Software Enterprises - Cases of French Software Companies

Journal of Technology Management & Innovation, 2015
Implementations of software production processes usually ignore organizational, market, and economical attributes of products that are to be inserted in international markets.
Maurício Floriano Galimberti, Raul Sidnei Wazlawick   +1 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Software Life Cycle

, 2008
The traditional software life cycle defined in ISO 12207 (Rada & Moore, 1997) begins with requirements capture and ends with retirement. The system development life cycle remains largely unchanged over the years, though it calls increasingly for end ...
Roy Rada
core   +1 more source

Exploring the role of generative AI in enhancing cybersecurity in software development life cycle

Array
Context: The rapid integration of Generative AI (GenAI) technologies in various sectors has introduced new opportunities and challenges. One of the areas where GenAI is gaining prominence is cybersecurity, particularly within the Software Development ...
Hussein A. Al-Hashimi, Rafiq Ahmad Khan, Hathal S. Alwageed, Asaad M. Algarni, Sarra Ayouni, Alaa Omran Almagrabi   +5 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source