Results 71 to 80 of about 29,727,043 (291)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

A Simulation Model for the Waterfall Software Development Life Cycle

open access: yesCoRR, 2012
Software development life cycle or SDLC for short is a methodology for designing, building, and maintaining information and industrial systems. So far, there exist many SDLC models, one of which is the Waterfall model which comprises five phases to be completed sequentially in order to develop a software solution.
openaire   +3 more sources

DATABASE DEVELOPMENT LIFE CYCLE [PDF]

open access: yes
A software development life cycle model (SDLC) consists of a set of processes (planning, requirements, design, development, testing, installation and maintenance) defined to accomplish the task of developing a software application that is functionally ...
Morgan D. Monger   +2 more
core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Environmentally conscious design : an economic life cycle approach [PDF]

open access: yes, 1997
Companies are under increasing pressure to deal with environmental concerns during product design, for it is the design process which primarily decides the environmental impact of a manufactured product over its life.
Rose, Elliot P.
core   +4 more sources

A comparative study of Software Development Life Cycle (SDLC) models [PDF]

open access: yes
Software Development life cycle (SDLC) is a framework model used in project management that defines the stages included in an information system and a software development project, from an initial feasibility study to the maintenance of the completed ...
Bajrami, Buen   +2 more
core  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Designing and quality testing of “Digichip” virtual simulation software of Android platform for mobile-virtual learning supporting vocational mechatronics engineering

open access: yesJurnal Pendidikan Vokasi, 2019
Technology enhancement in any life aspects is undeniably crucial to face the globalization era. A strategic approach to touch any life aspect is gained through education.
Titih Rejyasmito Hadi, Eko Marpanaji
doaj   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

Discussing Phases and Models of Software Development Life Cycle

open access: yesINTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT
Software Development is one of the most powerful, vital, and the need for an hour in today's generation. Every organization, industries, small firms, institutes, etc. require the software for the functionality of their system and reducing the manual work or the traditional work, which used to be insecure and had more errors.
Jyoti Sisodia, Dr.Suraj V Pote
openaire   +1 more source

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