Results 31 to 40 of about 793,066 (246)

Proposed ethical framework for software requirements engineering

IET Software, 2023
Requirements engineering is a fundamental process in software development phases. At the same time, it is a difficult phase and exposed many ethical violations. The main purpose is proposing an ethical framework for software requirements engineering that
Seblewongel E. Biable, Nuno M. Garcia, Dida Midekso   +2 more
doaj   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

Quality Management in Software Development

Advanced Engineering Research
Introduction. The scientific literature examines various approaches to quality management in information technology (IT). The issues of identifying and correcting defects are worked out, and the possibilities for minimizing them are shown.
M. D. Birulia
doaj   +1 more source

A Novel Software Engineering Approach Toward Using Machine Learning for Improving the Efficiency of Health Systems

IEEE Access, 2020
Recently, machine learning has become a hot research topic. Therefore, this study investigates the interaction between software engineering and machine learning within the context of health systems.
Mohammed Moreb, Tareq Abed Mohammed, Oguz Bayat   +2 more
doaj   +1 more source

Bayesian Decision Making of an Imperfect Debugging Software Reliability Growth Model with Consideration of Debuggers’ Learning and Negligence Factors

Mathematics, 2022
In this study, an imperfect debugging software reliability growth model (SRGM) with Bayesian analysis was proposed to determine an optimal software release in order to minimize software testing costs and also enhance the practicability.
Qing Tian, Chun-Wu Yeh, Chih-Chiang Fang
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

A predictive model for stunting among children under the age of three

Frontiers in Pediatrics
BackgroundIn light of the global effort to eradicate stunting in childhood, the objective of this research endeavor was to assess the prevalence of stunting and associated factors, simultaneously construct and validate a risk prediction model for ...
Yuxiang Xiong, Xuhuai Hu, Jindan Cao, Li Shang, Ben Niu, Ben Niu   +5 more
doaj   +1 more source

Software Release Assessment under Multiple Alternatives with Consideration of Debuggers’ Learning Rate and Imperfect Debugging Environment

Mathematics, 2022
In the software development life cycle, the quality and reliability of software are critical to software developers. Poor quality and reliability not only cause the loss of customers and sales but also increase the operational risk due to unreliable ...
Qing Tian, Chih-Chiang Fang, Chun-Wu Yeh
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source