Results 91 to 100 of about 4,581,706 (333)

Artificial intelligence approaches to software engineering [PDF]

Artificial intelligence approaches to software engineering are examined. The software development life cycle is a sequence of not so well-defined phases. Improved techniques for developing systems have been formulated over the past 15 years, but pressure
Johannes, James D., Macdonald, James R.
core   +1 more source

BOA: Framework for Automated Builds [PDF]

, 2003
Managing large-scale software products is a complex software engineering task. The automation of the software development, release and distribution process is most beneficial in the large collaborations, where the big number of developers, multiple ...
Ratnikova, N.
core   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

A Process Algebra Software Engineering Environment

, 2008
In previous work we described how the process algebra based language PSF can be used in software engineering, using the ToolBus, a coordination architecture also based on process algebra, as implementation model.
Diertens, B.
core  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Alinhando objetivos estratégicos e processo de desenvolvimento em empresas de software Aligning strategic objectives and development practices at software companies

Production, 2013
Sistemas de software são atualmente responsáveis por parte significativa das inovações tecnológicas viabilizadas em produtos e serviços. A história do software é recente, assim como são recentes as pesquisas sobre o tema, que tem como foco principal o ...
André Leme Fleury, Mauro de Mesquita Spinola, Fernando José Barbin Laurindo, Marcelo Schneck de Paula Pessôa   +3 more
doaj  

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

A Simulation Modeling Approach to Understanding the Software Development Process. [PDF]

, 1979
James A. McCall, Gain Wong, A. Stone
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Enhancing DevOps Engineering Education Through System-Based Learning Approach

Open Education Studies
System-based learning (SBL) in engineering domains integrates systems thinking and engineering principles to develop a system. In software engineering, to develop software using the DevOps process, using SBL environment, students gain a comprehensive ...
Zarour Mohammad, Akour Mohammed, Alenezi Mamdouh   +2 more
doaj   +1 more source