Results 91 to 100 of about 4,946,816 (331)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Application of a business process modeling architecture in software development

open access: yesVértices, 2010
Requirements definition in information systems projects has been done without support of more systematic methods that will guarantee development based on the business.
Delmir Peixoto de Azevedo Júnior   +1 more
doaj   +1 more source

Artificial intelligence approaches to software engineering [PDF]

open access: yes
Artificial intelligence approaches to software engineering are examined. The software development life cycle is a sequence of not so well-defined phases. Improved techniques for developing systems have been formulated over the past 15 years, but pressure
Johannes, James D., Macdonald, James R.
core   +1 more source

A systematic approach for component-based software development [PDF]

open access: yes, 2000
Component-based software development enables the construction of software artefacts by assembling prefabricated, configurable and independently evolving building blocks, called software components.
Ferreira Pires, L.   +2 more
core   +3 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Secure Scrum: Development of Secure Software with Scrum

open access: yes, 2015
Nowadays, the use of agile software development methods like Scrum is common in industry and academia. Considering the current attacking landscape, it is clear that developing secure software should be a main concern in all software development projects.
Hof, Hans-Joachim, Pohl, Christoph
core  

BOA: Framework for Automated Builds [PDF]

open access: yes, 2003
Managing large-scale software products is a complex software engineering task. The automation of the software development, release and distribution process is most beneficial in the large collaborations, where the big number of developers, multiple ...
Ratnikova, N.
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

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