Results 61 to 70 of about 6,082,654 (289)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Software requirement engineering over the federated environment in distributed software development process

Journal of King Saud University: Computer and Information Sciences
In the recent past, the distributed software development (DSD) process has become increasingly prevalent with the rapid evolution of the software development process.
Abdulaziz Alhumam, Shakeel Ahmed
doaj   +1 more source

QUALITY OF THE SOFTWARE DEVELOPMENT PROCESS

IFAC Proceedings Volumes, 1983
Abstract The goal of Software Quality Assurance is to ensure that the software product meets the imposed quality requirements. In embedded real-time systems, such as power system operation control, the quality requirements on software are high and steadily increasing with the degree of computerization.
K. Frühauf, H. Sandmayr
openaire   +1 more source

A systematic mapping study on the open source software development process

International Conference on Evaluation & Assessment in Software Engineering, 2012
Background: There is no globally accepted open source software development process to define how open source software is developed in practice. A process description is important for coordinating all the software development activities involving both ...
S. T. Acuña, John W. Castro, Óscar Dieste Tubío, Natalia Juristo Juzgado   +3 more
semanticscholar   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Software Development Process Changes in the Telecommunications Industry [PDF]

Journal of Systemics, Cybernetics and Informatics, 2006
The tremendous changes in the telecommunications business in the last several years drove changes in the software development processes of telecommunications equipment providers.
John Kevin Doyle, Robert S. Janek, M. David Long   +2 more
doaj  

MaTGeC: hacia un marco de trabajo para la gestion cuantitativa de procesos de desarrollo de software en pequeñas organizacione

Tecnura, 2014
The small software development companies have difficulties in adopting practices about quantitative process management offered by reference models such as CMMI-DEV or ISO/IEC 15504 because it generates expensive investments in long-term periods of time ...
Carlos Alberto Ardila Albarracin, Francisco José Pino Correa, César Jesús Pardo Calvache, Luis Merchán Paredes   +3 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Causal analysis procedure focused on small software development organizations

Revista Facultad de Ingeniería, 2017
Very Small Entities (VSE) dedicated to software development lack of enough resources to adopt causal analysis practices, defined in models as CMMI, due to their complexity and costs.
Kelly Yohanna Zúñiga-Silva, Carlos Alberto Ardila-Albarracín, Francisco José Pino-Correa   +2 more
doaj   +1 more source