Results 61 to 70 of about 4,581,706 (333)

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

open access: yesFEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli   +10 more
wiley   +1 more source

Factors Models of Scrum Adoption in the Software Development Process: A Systematic Literature Review [PDF]

open access: yesReCIBE, 2018
(Background) The adoption of Agile Software Development (ASD), in particular Scrum, has grown significantly since its introduction in 2001. However, in Lima, many ASDs implementations have been not suitable (uncompleted or inconsistent), thus losing ...
Marilyn Sihuay   +2 more
doaj  

Scope Management of Non-Functional Requirements [PDF]

open access: yes, 2007
In order to meet commitments in software projects, a realistic assessment must be made of project scope. Such an assessment relies on the availability of knowledge on the user-defined project requirements and their effort estimates and priorities, as ...
Daneva, M., Kassab, M., Ormandjieva, O.
core   +3 more sources

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

open access: yesFEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter   +8 more
wiley   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

MaTGeC: hacia un marco de trabajo para la gestion cuantitativa de procesos de desarrollo de software en pequeñas organizacione

open access: yesTecnura, 2014
The small software development companies have difficulties in adopting practices about quantitative process management offered by reference models such as CMMI-DEV or ISO/IEC 15504 because it generates expensive investments in long-term periods of time ...
Carlos Alberto Ardila Albarracin   +3 more
doaj   +1 more source

Design Criteria to Architect Continuous Experimentation for Self-Driving Vehicles

open access: yes, 2017
The software powering today's vehicles surpasses mechatronics as the dominating engineering challenge due to its fast evolving and innovative nature.
Berger, Christian, Giaimo, Federico
core   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

open access: yesFEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász   +6 more
wiley   +1 more source

Validation in the Software Metric Development Process [PDF]

open access: yes, 1995
In this paper the validation of software metrics will be examined. Two approaches will be combined: representational measurement theory and a validation network scheme.
Berg, K.G. van den, Broek, P.M. van den
core   +2 more sources

The Unified Approach For Organizational Network Vulnerability Assessment

open access: yes, 2013
The present business network infrastructure is quickly varying with latest servers, services, connections, and ports added often, at times day by day, and with a uncontrollably inflow of laptops, storage media and wireless networks.
Jagli, Mrs. Dhanamma   +1 more
core   +1 more source

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