Network Localization of Fatigue in Multiple Sclerosis
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo +12 more
wiley +1 more source
Improvement of effort estimation accuracy in software projects using a feature selection approach [PDF]
In recent years, utilization of feature selection techniques has become an essential requirement for processing and model construction in different scientific areas.
Zahra Shahpar +3 more
doaj
Frailty Exacerbates Disability in Progressive Multiple Sclerosis
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks +10 more
wiley +1 more source
Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer +14 more
wiley +1 more source
Using Machine Learning and Simplified Functional Measures to Estimate Software Development Effort
Functional size measures are often used as the basis for estimating development effort, because they are available in the early stages of software development.
Luigi Lavazza +2 more
doaj +1 more source
Software productivity and effort estimation [PDF]
Jens Heidrich +2 more
openaire +1 more source
Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort
ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen +11 more
wiley +1 more source
Review and Empirical Analysis of Machine Learning-Based Software Effort Estimation
The average software company spends a huge amount of its revenue on Research and Development (R&D) for how to deliver software on time. Accurate software effort estimation is critical for successful project planning, resource allocation, and on ...
Mizanur Rahman +4 more
doaj +1 more source
A software benchmarking methodology for effort estimation [PDF]
Yazılım proje yöneticileri genellikle iş gücü, maliyet ve yazılım geliştirme süresini tahmin etmek için referans veri kümelerini kullanırlar. Bu tahminler proje faaliyetlerinin uygun planlama, izleme, ve kontrolü için kullanılır. İş gücü kestirimi yazılım geliştirme projesinin başarısında önemli bir rol oynamaktadır ve referans veri kümesinin kalitesi ...
openaire +1 more source
The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley +1 more source

