Results 131 to 140 of about 8,130,795 (304)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Requirements Engineering: In Search of the Dependent Variables

open access: yes, 2008
When software development teams modify their requirements engineering process as an independent variable, they often examine the implications of these process changes by assessing the quality of the products of the requirements engineering process,
Davis, Alan, Gorschek, Tony
core   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Bots in software engineering: a systematic mapping study. [PDF]

open access: yesPeerJ Comput Sci, 2022
Santhanam S   +3 more
europepmc   +1 more source

Global software engineering experience through international capstone project exchanges

open access: yes, 2018
Today it is very common for software systems to be built by teams located in more than one country. For example, a project team may be located in the US while the team lead resides in Sweden.
Ginige, Jeewani Anupama,   +42 more
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

ISRN Software Engineering

open access: yes, 2011
ISSN: 2090-7672 (Print) ISSN: 2090-7680 (Online) doi:10.5402/SE I am a member of the editorial board ISRN Software Engineering is a peer-reviewed, open access journal that publishes original research articles as well as review articles in all areas of ...
CIANCARINI, PAOLO
core   +1 more source

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