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Fatal Software Failures in Spaceflight

Encyclopedia
Space exploration has become an integral part of modern society, and since its early days in the 1960s, software has grown in importance, becoming indispensable for spaceflight.
Christian R. Prause, Ralf Gerlich, Rainer Gerlich   +2 more
doaj   +1 more source

e-CF Competences in Software Engineering Course

Applied Computer Systems, 2019
The article describes the definition of competences formed during the acquisition of the study course “Software Engineering” at Riga Technical University. The European e-Competence Framework (e-CF) is adopted for this purpose.
Zaitseva Larisa
doaj   +1 more source

Guest Editorial: Intelligence for systems and software engineering. [PDF]

Innov Syst Softw Eng, 2023
Hinchey M, Jain A, Kaushik M, Misra S.
europepmc   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Human-centred cyber secure software engineering. [PDF]

Z Arbeitswiss, 2023
Renaud K.
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Reverse Engineering in Data Integration Software [PDF]

Database Systems Journal, 2013
Integrated applications are complex solutions that help build better consolidated and standardized systems from existing (usually transactional) systems.
Vlad DIACONITA
doaj  

Using Software Engineering Concepts And Techniques To Leverage Learning: A Novel Approach [PDF]

, 2020
Zhong Wei Gu, Sheela Ramanna, James F. Peters, Hal Berghel, Daniel Berleant, Steve F. Russell   +5 more
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Psychological Types of Brazilian Software Engineering Students [PDF]

, 2015
Luiz Fernando Capretz
openalex   +1 more source