Results 141 to 150 of about 5,528,326 (333)
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Gamification in software engineering: the mediating role of developer engagement and job satisfaction. [PDF]
Stol KJ, Schaarschmidt M, Goldblit S.
europepmc +1 more source
Integrating Risk Into An Engineering Economy Course With Simulation Software [PDF]
Rita L. Endt, Eyler Robert Coates
openalex +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Flexibility in Research Designs in Empirical Software Engineering [PDF]
Vigdis By Kampenes +2 more
openalex +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Trends in Intelligent and AI-Based Software Engineering Processes: A Deep Learning-Based Software Process Model Recommendation Method. [PDF]
Alshammari FH.
europepmc +1 more source

