Results 31 to 40 of about 900,402 (262)

Tracking Health Related Quality of Life From Diagnosis to Follow‐Up Among Australian Children With Acute Lymphoblastic Leukaemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukaemia (ALL) is one of the most treatable forms of paediatric cancer; however, there is a substantial burden of treatment‐related toxicities (TRTs). In addition, the long‐term changes in children's health‐related quality of life (HRQoL) due to toxic treatments are not well understood.
Clare Ghows, Clarissa E. Schilstra, Karen McCleary, Nancy E. Briggs, Rishi S. Kotecha, Richard De Abreu Lourenco, Shanti Ramachandran, Ruelleyn Cockcroft, Rachel Conyers, Siobhan Cross, Luciano Dalla‐Pozza, Peter Downie, Tamas Revesz, Michael Osborn, Frank Alvaro, Claire E. Wakefield, Glenn M. Marshall, Toby Trahair, Marion K. Mateos, Joanna E. Fardell   +19 more
wiley   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Software requirement engineering over the federated environment in distributed software development process

Journal of King Saud University: Computer and Information Sciences
In the recent past, the distributed software development (DSD) process has become increasingly prevalent with the rapid evolution of the software development process.
Abdulaziz Alhumam, Shakeel Ahmed
doaj   +1 more source

An Activity Theory-Based Approach for Context Analysis, Design and Evolution

Applied Sciences, 2022
This paper presents a new interdisciplinary approach to support context modeling in context-awareness software developments. The premise of this approach relies on the idea that understanding a complex socio-technical ecology, while adapting the software
Ismael Camargo-Henríquez, Andrés Silva
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Gender in Software Engineering

IEEE Software, 2019
The topic of gender in software engineering received significant attention during the most recent International Conference on Software Engineering (ICSE). Papers related to gender appeared in the main research track, the Software Engineering in Society (SEIS) track, and the second Gender Equity (GE) workshop (https://sites.google.com/view/ge-icse2019).
Jeffrey C. Carver, Alexander Serebrenik
openaire   +1 more source

An Empirical Study on Software Test Effort Estimation for Defense Projects

IEEE Access, 2022
Effort estimation of software testing plays a vital role in the effective completion of testing. In particular, software test effort estimation in defense projects is not an easy and simple phenomenon, owing to internal and external factors.
Esra Cibir, Tulin Ercelebi Ayyildiz
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Model of Internet System Client Service [PDF]

Computer Science, 2003
At present, service of different kinds of internet clients involves necessity of defining their behaviour in various situations. To determine optimal solutions it is purposeful to know and to describe objectively their behaviour by means of mathematical ...
Tomasz Rak
doaj