Results 81 to 90 of about 7,357,569 (397)

Elucidation of interface interactions between a dehydratase domain and an acyl carrier protein in cremimycin polyketide synthase

open access: yesFEBS Letters, EarlyView.
In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri   +8 more
wiley   +1 more source

Software Development Cost Estimation Methods [PDF]

open access: yesComputer Science, 2003
Early estimation of project size and completion time is essential for successful project planning and tracking. Multiple methods have been proposed to estimate software size and cost parameters.
Bogdan Stepien
doaj  

Documenting research software in engineering science

open access: yesScientific Reports, 2022
The reuse of research software needs good documentation, however, the documentation in particular is often criticized. Especially in non-IT specific disciplines, the lack of documentation is attributed to the lack of training, the lack of time or missing
Sibylle Hermann, Jörg Fehr
doaj   +1 more source

An Agile Software Engineering Method to Design Blockchain Applications [PDF]

open access: yesCentral and Eastern European Software Engineering Conference in Russia, 2018
Cryptocurrencies and their foundation technology, the Blockchain, are reshaping finance and economics, allowing a decentralized approach enabling trusted applications with no trusted counterpart.
M. Marchesi   +2 more
semanticscholar   +1 more source

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

open access: yesFEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung   +6 more
wiley   +1 more source

Trends in Modern Exception Handling [PDF]

open access: yesComputer Science, 2003
Exception handling is nowadays a necessary component of error proof information systems. The paper presents overview of techniques and models of exception handling, problems connected with them and potential solutions.
Marcin Kuta
doaj  

Software Engineering Team Project - lessons learned [PDF]

open access: yese-Informatica Software Engineering Journal, 2013
In the 2010/11 academic year the Institute of Informatics at Wroclaw University of Technology issued ’Software Engineering Team Project’ as a course being a part of the final exam to earn bachelor’s degree.
Bogumiła Hnatkowska
doaj   +1 more source

An Empirical Study on Software Test Effort Estimation for Defense Projects

open access: yesIEEE Access, 2022
Effort estimation of software testing plays a vital role in the effective completion of testing. In particular, software test effort estimation in defense projects is not an easy and simple phenomenon, owing to internal and external factors.
Esra Cibir, Tulin Ercelebi Ayyildiz
doaj   +1 more source

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

open access: yesFEBS Letters, EarlyView.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher   +6 more
wiley   +1 more source

On Telecommunication Software Engineering Education [PDF]

open access: yesProceedings of the XXth Conference of Open Innovations Association FRUCT, 2017
Communication specialists around the world are facing the same problem: shifting from circuit switching to packet switching. In 2006, the Pentagon adopted a new plan for the next 15 years entitled Joint Vision 2020.
Manfred Sneps-Sneppe   +2 more
doaj  

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