Results 121 to 130 of about 676,694 (342)
Discover Applied SciencesIn response to the problem of poor imaging quality caused by amplitude and phase errors in synthetic aperture imaging, this study develops an aperture radar-assisted technology based on an array of mathematical models and statistical characteristic ...
Ji Yang, Ying Fan, Shuqing Yang
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Guidelines for Using Empirical Studies in Software Engineering Education [PDF]
, 2018 Software engineering education is under constant pressure to provide students with industry-relevant knowledge and skills. Educators must address issues beyond exercises and theories that can be directly rehearsed in small settings. Industry training has
Fagerholm, Fabian +2 more
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Kurikul za praktično visoko obrazovanje programskih inženjera [PDF]
, 2012 Mishra, Deepti/0000-0001-5144-3811; Mishra, Alok/0000-0003-1275-2050Software engineering is the fastest-evolving engineering discipline and most of the tasks of software development organizations are diverse in nature.
Mishra, Deepti, Mishra, Alok
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آموزش مهندسی ایرانEngineering education, alongside various fields of engineering, requires research and importance. In engineering sciences, numerical simulation using computer software is one of the important research tools for engineers.
Mansouri Amirhosein +1 more
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Model Driven Software Engineering in Education: A Multi-Case Study on Perception of Tools and UML [PDF]
, 2017 While several benefits of using models in software engineering have been observed in practice, the adoption of modeling remains low. Multiple challenges of using models, especially related to tools, have been reported both for industrial use and for ...
Omar Badreddin +9 more
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ACM Transactions on Computing Education, 2019 We are pleased to introduce this Special Issue on Global Software Engineering Education published by the ACM Transactions on Computing Education (TOCE) that focuses on educational practices to prepare students for a global workplace.
T. Clear, Sarah Beecham
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
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