Results 21 to 30 of about 387,273 (262)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Educational digital resource for data analysis of Civil Engineering laboratory tests
Modelling in Science Education and Learning, 2018 This work aims to implement and evaluate an interactive educational software that helps Civil Engineering students to perform and analyze the calculations related to different Soil Mechanics laboratory tests.
Gustavo Henrique Nalon +2 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
InformaticsThe excessive and inappropriate use of the internet by children and young people increases their exposure to risky situations, especially since the COVID-19 pandemic.
Yasiel Pérez Vera +2 more
doaj +1 more source
Jurnal Teknologi dan Sistem Komputer, 2016 System computer engineering of Diponegoro University has a software engineering laboratory fonctioned to provide the learning and training activities in order to give the opportunity for the students, to examine and to apply the theory or the research ...
Faiz Risaludin Islami +2 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Rejoinder: Software Engineering and R Programming
The R Journal, 2021 It is a pleasure to take part in such fruitful discussion about the relationship between Software Engineering and R programming, and what could be gain by allowing each to look more closely at the other.
openaire +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Evaluating User Experience E-Commerce Platform Using Hassenzahl Framework
International Journal of Applied Sciences and Smart TechnologiesThe Hassenzahl framework of UX provides an approach in measuring user experience of a product which covers such the following aspects : be goals, do goals, and motor goals.
Stevanus Wisnu Wijaya +1 more
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source